Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/18152
Title: Analysis of shared heritability in common disorders of the brain.
Authors: Anttila, Verneri;Bulik-Sullivan, Brendan;Finucane, Hilary K;Walters, Raymond K;Bras, Jose;Duncan, Laramie;Escott-Price, Valentina;Falcone, Guido J;Gormley, Padhraig;Malik, Rainer;Patsopoulos, Nikolaos A;Metspalu, Andres;Chen, Wei-Min;Waddington, John;Walters, James;Weiser, Mark;Andlauer, Till F M;Cheng, Wei;Sonnen, Joshua A;Cormand, Bru;Schreiber, Stefan;Poon, Wayne W;Berr, Claudine;Cloninger, Robert;Curtis, David;Gejman, Pablo V;Henskens, Frans;Mattingsdal, Morten;Hannequin, Didier;Forstner, Andreas J;Kubisch, Christian;Oh, Sang-Yun;Macaya, Alfons;De Rubeis, Silvia;Scott, Rodney;Webb, Bradley;Parr, Jeremy;Ramos-Quiroga, Josep Antoni;Breen, Gerome;Churchhouse, Claire;Stern, Robert A;Bulik, Cynthia M;Streit, Fabian;Konkashbaev, Anuar;Daly, Mark;Turecki, Gustavo;Dichgans, Martin;Mitchell, Braxton;Faraone, Stephen V;Ferrari, Michel D;Regan, Regina;Guerreiro, Rita;Sánchez-Mora, Cristina;Holmans, Peter;Lanzagorta, Nuria;Kendler, Kenneth S;Gibbs, Raphael;Letenneur, Luc;Koeleman, Bobby;Mathews, Carol A;Price, Alkes;Van Deerlin, Vivianna M;Scharf, Jeremiah;Rothwell, Peter;Hakonarson, Hakon;Valencia-Duarte, Ana;Sklar, Pamela;Williams, Julie;Goate, Alison M;Huyser, Chaim;Baune, Bernhard T;Belin, Andrea C;Wood, Nicholas W;Cotsapas, Chris;Palotie, Aarno;Smoller, Jordan W;Leboyer, Marion;Sullivan, Patrick;Rosand, Jonathan;Reichenberg, Abraham;Corvin, Aiden;Illmann, Cornelia;Sharma, Pankaj;Air, Tracy;Van Eldik, Linda J;Striano, Pasquale;Neale, Benjamin M;Bramon, Elvira;Schott, Jonathan M;van den Maagdenberg, Arn M J M;Anney, Richard;Elia, Josephine;Grigoroiu-Serbanescu, Maria;Jenike, Michael;Sandin, Sven;Edenberg, Howard J;Battaglia, Agatino;Murray, Robin;Buccola, Nancy;Harold, Denise;Sudlow, Cathie;Ribasés, Marta;Russo, Giancarlo;Rubinsztein, David C;Bayer, Anthony;Kuperman, Samuel;Tsolaki, Magda;Lee, Phil H;Vorstman, Jacob;Attia, John;Wedenoja, Juho;Proitsi, Petra;Fox, Nick C;Hampel, Harald;Owen, Michael J;Mead, Simon;Ripke, Stephan;Leventhal, Bennett;Vicente, Astrid;Passmore, Peter;Demirci, F Yesim;Morgan, Kevin;Nöthen, Markus M;Sinnamon, Grant;Wassink, Thomas;Rossor, Martin;Lupton, Michelle K;Zwart, John-Anker;Hoffmann, Per;Leverenz, James B;Kornhuber, Johannes;Greenberg, Erica;Lawlor, Brian;Casas, Miguel;McQuillin, Andrew;Markus, Hugh;Wray, Naomi R;Al-Chalabi, Ammar;Wijsman, Ellen;Bis, Joshua C;Ruiz, Agustin;Schosser, Alexandra;Buring, Julie E;Boada, Mercè;Seshadri, Sudha;Beiser, Alexa;Boomsma, Dorret;Rice, Kenneth;Hervas, Amaia;Huang, Hailiang;van der Lee, Sven J;De Jager, Philip L;Vepsäläinen, Salli;Cahn, Wiepke;Lochner, Christine;Kourkoulis, Christina;Geschwind, Daniel H;Riemenschneider, Matthias;Riedel-Heller, Steffi;Rotter, Jerome I;Ransmayr, Gerhard;Hyman, Bradley T;Head, Elizabeth;Cruchaga, Carlos;Cairns, Murray;Arranz, Maria Jesús;Lyon, Gholson J;Eriksson, Nicholas;Julià, Antonio;Alegret, Montserrat;Winsvold, Bendik;Pera, Joana;Palta, Priit;Farh, Kai-How;Cuenca-Leon, Ester;Chong, Siow A;MacIntyre, Donald J;Furlotte, Nicholas;Ophoff, Roel;Kurth, Tobias;Olesen, Jes;Haavik, Jan;Cook, Edwin;Chasman, Daniel I;Nyholt, Dale R;Avbersek, Andreja;Cohen, David;Baum, Larry;Ran, Caroline;Porteous, David;Heinzen, Erin L;Berkovic, Samuel F;Bradfield, Jonathan;Turley, Patrick;Buono, Russell;Catarino, Claudia B;Ligthart, Lannie;Crespo-Facorro, Benedicto;Zayats, Tetyana;Cossette, Patrick;De Jonghe, Peter;Depondt, Chantal;Macciardi, Fabio;Homuth, Georg;Dlugos, Dennis;Ferraro, Thomas N;Raffeld, Miriam;French, Jacqueline;Pozo-Rosich, Patricia;Hjalgrim, Helle;Jamnadas-Khoda, Jennifer;Santangelo, Susan;Grenier-Boley, Benjamin;Johansson, Stefan;Madruga-Garrido, Marcos;Kälviäinen, Reetta;Rivera, Margarita;Kunz, Wolfram S;Lerche, Holger;Levitt, Pat;Leu, Costin;Lindhout, Dick;Lo, Warren;Silliman, Scott;Lowenstein, Daniel;Delorme, Richard;Ryten, Mina;McCormack, Mark;Møller, Rikke S;Heutink, Peter;Quinn, Joseph F;Williams, Nigel;Molloy, Anne;Chouraki, Vincent;Ng, Ping-Wing;Oliver, Karen L;Privitera, Michael;Radtke, Rodney;Salomaa, Veikko;Ruppert, Ann-Kathrin;Rogé, Bernadette;Crowley, James;Amouyel, Philippe;Betancur, Catalina;Sander, Thomas;Schachter, Steven;Dempfle, Astrid;Schankin, Christoph;Scheffer, Ingrid E;Schoch, Susanne;Malaty, Irene A;Kamatani, Yoichiro;Kaye, Jeffrey A;Sisodiya, Sanjay M;Boraska Perica, Vesna;Magalhaes, Tiago;Grove, Jakob;Thornton, Laura M;Huckins, Laura M;William Rayner, N;Lewis, Cathryn M;Surges, Rainer;Maras, Athanasios;Espeseth, Thomas;Gratacos, Monica;Rybakowski, Filip;Gordon, Scott D;Keski-Rahkonen, Anna;Raevuori, Anu;Smith, Philip;Kukull, Walter A;Hudson, James I;Boland, Anne;Reichborn-Kjennerud, Ted;Davidson, Michael;McGrath, Lauren;Monteleone, Palmiero;Karwautz, Andreas;Rothenberger, Aribert;Mannik, Katrin;Baker, Jessica H;O'Toole, Julie K;Middeldorp, Christel M;Borck, Guntram;Arking, Dan;DeLisi, Lynn;Trace, Sara E;Miguel, Eurípedes C;Davis, Oliver S P;Helder, Sietske G;Ehrlich, Stefan;Deleuze, Jean-François;Herpertz-Dahlmann, Beate;Huentelman, Matthew J;Danner, Unna N;Hickie, Ian;Mitchell, James;van Elburg, Annemarie A;Clementi, Maurizio;Alfredsson, Lars;Schulze, Thomas G;Forzan, Monica;Adams, Hieab H H;Docampo, Elisa;Lissowska, Jolanta;Hauser, Joanna;Tortorella, Alfonso;Battey, Thomas;Maj, Mario;Pergadia, Michele;Schürks, Markus;Pato, Carlos;Duron, Emmanuelle;Gonidakis, Fragiskos;Thompson, Robert C;Tziouvas, Konstantinos;Papezova, Hana;Yilmaz, Zeynep;Dinan, Timothy;Lehtimäki, Terho;Wagner, Gudrun;Kuntsi, Jonna;Mehta, Divya;Mir, Pablo;Oades, Robert D;Banaschewski, Tobias;Franke, Barbara;Buitelaar, Jan K;Rabionet, Raquel;Donohoe, Gary;Arias Vasquez, Alejandro;Doyle, Alysa E;Thomas, G Neil;Reif, Andreas;Lesch, Klaus-Peter;Cohen-Woods, Sarah;Huang, Jie;Freitag, Christine;Hrafnsdottir, Maria;Kamboh, M Ilyas;Drapeau, Elodie;Rivero, Olga;Palmason, Haukur;Strohmaier, Jana;Romanos, Marcel;Langley, Kate;Rietschel, Marcella;Nestadt, Gerald;Visscher, Frank;Smit, Johannes H;Witt, Stephanie H;Duan, Jubao;Dalsgaard, Soeren;Børglum, Anders D;Waldman, Irwin;Hottenga, Jouke-Jan;Wilmot, Beth;Martin, Nicholas G;Larson, Eric B;Levey, Allan I;Molly, Nikolas;Bau, Claiton H D;Maestrini, Elena;Hulette, Christine M;Crosbie, Jennifer;Whelan, Christopher D;Schachar, Russell;Loo, Sandra K;McGough, James J;Grevet, Eugenio H;Medland, Sarah E;Nicolini, Humberto;Marson, Anthony;Hanna, Gregory L;Penninx, Brenda;Robinson, Elise;Jansen, Rick;Weiss, Lauren A;Rogaeva, Ekaterina;Bacchelli, Elena;Zara, Federico;Bailey, Anthony;Matthews, Keith;Okun, Michael S;Haan, Lieuwe;Melle, Ingrid;Morris, Derek;Blackwood, Douglas;McIntosh, Andrew;Bolton, Patrick;Bergen, Sarah E;Farrer, Lindsay A;Dick, Danielle M;Schalling, Martin;Jamain, Stéphane;Bal, Vanessa;Mok, Kin Y;Maaser, Anna;Becker, Felicitas;Montgomery, Grant W;Fischer, Sascha B;Reinbold, Céline S;de Geus, Eco;Fullerton, Janice M;Guzman-Parra, José;Mayoral, Fermin;Hougaard, David;Vardarajan, Badri N;Pakstis, Andrew;Schofield, Peter R;Cichon, Sven;Barnes, Lisa L;Mühleisen, Thomas W;Stroink, Hans;Degenhardt, Franziska;Martinez, Maria;Kurki, Mitja I;Hansen, Thomas;Schumacher, Johannes;Bauer, Michael;Loehrer, Elizabeth;Mitchell, Philip B;Ripatti, Samuli;Gershon, Elliot S;Rice, John;Potash, James B;Zandi, Peter P;Craddock, Nick;Karachanak-Yankova, Sena;Lundervold, Astri J;Zimprich, Fritz;Beach, Thomas G;Paschou, Peristera;Ferrier, I Nicol;Wei, Zhi;Alda, Martin;Andreassen, Ole A;Rouleau, Guy A;Dunn, Erin;Saykin, Andrew J;Li, Qingqin S;Nauck, Matthias;Schoevers, Robert A;Beekman, Aartjan Tf;Anjorin, Adebayo;Knowles, James A;Sandor, Cynthia;Cantor, Rita;Viktorin, Alexander;Arnold, Paul;Strober, Michael;Jicha, Gregory A;Steen, Vidar M;Morris, Huw R;Barr, Cathy L;Bedoya-Berrio, Gabriel;Piacentini, John;Bienvenu, O Joseph;Brentani, Helena;Burton, Christie;Artto, Ville;Khrunin, Andrey;Camarena, Beatriz;Cappi, Carolina;Webber, Caleb;Cath, Danielle;Pinto, Dalila;Cavallini, Maria;Reitz, Christiane;Sharma, Manu;Cusi, Daniele;Kauwe, John S K;Boncoraglio, Giorgio;Darrow, Sabrina;Celestino-Soper, Patrícia;Denys, Damiaan;Derks, Eske M;Dietrich, Andrea;Fernandez, Thomas;Figee, Martijn;St George-Hyslop, Peter;Scherer, Stephen W;Muller-Myhsok, Bertram;Klovins, Janis;Freimer, Nelson;Terwindt, Gisela M;Gerber, Gloria;Dawson, Geraldine;Grados, Marco;Pittenger, Christopher;Plessen, Kerstin;Ramensky, Vasily;Ramos, Eliana M;Reus, Victor;Hartmann, Andreas;Lieberman, Andrew P;Pulit, Sara;Stahl, Eli;Richter, Margaret A;Riddle, Mark A;Göbel, Hartmut;Duque, Frederico;Padyukov, Leonid;Robertson, Mary M;Roessner, Veit;Kučinskas, Vaidutis;Rosário, Maria;Samuels, Jack F;Sandor, Paul;Gasser, Thomas;Stein, Dan J;Tsetsos, Fotis;Bevan, Steve;Van Nieuwerburgh, Filip;Green, Andrew;Pankratz, Vernon S;Kaunisto, Mari;Halmi, Katherine A;Weatherall, Sarah;Yu, Dongmei;Wendland, Jens R;Leber, Markus;Wolanczyk, Tomasz;Worbe, Yulia;Zai, Gwyneth;Goes, Fernando S;McLaughlin, Nicole;Hämäläinen, Eija;Klauck, Sabine M;Holliday, Elizabeth;Nestadt, Paul S;Sperling, Michael;Grabe, Hans-Jorgen;Czerski, Piotr M;Depienne, Christel;Lee Chee Keong, Jimmy;Limborska, Svetlana;Loughland, Carmel;Lönnqvist, Jouko;Maher, Brion;Werge, Thomas;Bergen, Andrew W;Hirschtritt, Matthew E;Mattheisen, Manuel;McDonald, Colm;Thijs, Vincent N;Cruceanu, Cristiana;Mane, Shrikant;Schneider, Lon S;Murphy, Kieran C;Nenadic, Igor;van Os, Jim;Pantelis, Christos;Aschauer, Harald;Pato, Michele;Petryshen, Tracey;Kaye, Walter;Quested, Digby;Jones, Ian R;Kaprio, Jaakko;De-Luca, Daniel Moreno-;Roussos, Panos;Freilinger, Tobias;Sanders, Alan R;Hoekstra, Pieter J;Schall, Ulrich;Smith, Amanda G;Schwab, Sibylle G;Sim, Kang;So, Hon-Cheong;Posthuma, Danielle;Szatkiewicz, Jin Peng;Stögmann, Elisabeth;Herms, Stefan;Subramaniam, Mythily;Huang, Alden;Toncheva, Draga
Affiliation: School of Nursing, Louisiana State University Health Sciences Center, New Orleans, LA, USA
Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA
Division of Adolescent and Child Psychiatry, Department of Psychiatry, LaUSAnne University Hospital, LaUSAnne, Switzerland
Child and Adolescent Mental Health Centre, Mental Health Services Capital Region Copenhagen, University of Copenhagen, Copenhagen, Denmark
Moscow Institute of Physics and Technology, Dolgoprudny, Institusky 9, Moscow, Russia
Department of Psychiatry, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
Frederick W. Thompson Anxiety Disorders Centre, Sunnybrook Health Sciences Centre, Toronto, Canada
Department of Psychiatry, University of Toronto, Toronto, Canada
Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands
Division of Neuropsychiatry, University College London, London, UK
Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technischen Universität Dresden, Dresden, Germany
Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany
MRC Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK
Departments of Psychiatry and of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA
UCL Institute of Neurology, London, UK
Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA
School of Biotechnology, Dublin City University, Glasnevin, Dublin, Ireland
Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK
Division Biomedical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands
Department of Psychiatry and UF Genetics Institute, University of Florida, Gainesville, FL, USA
Laboratory of Pharmaceutical Biotechnology, Ghent University, Ghent, Belgium
The Warren Alpert Medical School of Brown University, Providence, RI, USA
McKnight Brain Institute, University of Florida, Gainesville, FL, USA
Division of Cognitive and Behavioral Neurology, Brigham and Women's Hospital, Boston, MA, USA
Genes and Disease Programme, Centre for Genomic Regulation (CRG), Barcelona, Spain
University of New Mexico Health Sciences Center, Albuquerque, NM, USA
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
Department of Neurology, Yale School of Medicine, New Haven, CT, USA
Institute for Molecular Medicine Finland (FIMM), HiLIFE, University of Helsinki, Helsinki, Finland
Department of Genetics and Psychiatry, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA. verneri.anttila@gmail.com acorvin@tcd.ie bneale@broadinstitute.org
Neuropsychiatric Genetics Research Group, Department of Psychiatry, Trinity College Dublin, Dublin, Ireland
Danish Headache Center, Rigshospitalet Glostrup and University of Copenhagen, Copenhagen, Denmark
Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands
Centre for Genomic Sciences, University of Hong Kong, Hong Kong
Institute of Human Genetics, University of Bonn, Bonn, Germany
Functional Genomics Center Zurich, ETH/UZH-Zurich, Zurich, Switzerland
Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA. verneri.anttila@gmail.com acorvin@tcd.ie bneale@broadinstitute.org
Institute of Medical Informatics and Statistics, Kiel University, Kiel, Germany
Dementia Research Centre, UCL Institute of Neurology, London, UK
Department of Pediatrics, Nemours A.I. duPont Hospital for Children, Wilmington, DE, USA
Department of Psychiatry, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA
Laboratory of Psychiatric Neurobiology, Institute of Molecular Medicine, I.M. Sechenov First Moscow State Medical University, Moscow, Russia
Vilnius University, Vilnius, Lithuania
Department of Translational Psychiatry, School for Mental Health and Neuroscience (MHeNS), Maastricht University, Maastricht, The Netherlands
Pfizer, Inc., New York, NY, USA
Division of Molecular Psychiatry, Center of Mental Health, University of Wuerzburg, Wuerzburg, Germany
Department of Adult Psychiatry, Poznan University of Medical Sciences, Poland
Alexandru Obregia Clinical Psychiatric Hospital, Biometric Psychiatric Genetics Research Unit, Bucharest, Romania
Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA
Department of Medical Genetics, Cambridge Institute for Medical Research, Cambridge, UK
UK Dementia Research Institute, Cambridge, UK
School of Medicine, Cardiff University, Cardiff, UK
Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
Institute of Mental Health, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore
1st and 3rd Departments of Neurology, Aristotle University of Thessaloniki, Thessaloniki, Greece
Greek Association of Alzheimer's Disease and Related Disorders, Thessaloniki, Greece
Clinic for Child and Adolescent Psychiatry and Psychotherapy, University of Duisburg-Essen, Essen, Germany
Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK
Advanced Interventions Service, NHS Tayside, Dundee, UK
Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France
Institute of Memory and Alzheimer's Disease (IM2A), Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France
Brain & Spine Institute (ICM), INSERM U 1127, CNRS UMR 7225, Paris, France
AXA Research Fund & Sorbonne University Chair, Paris, France 
Department of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia
Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany
MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK
Department of Child Psychiatry, Medical University of Warsaw, Warsaw, Poland
Institute of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, UK
Clinicum, Department of Public Health, University of Helsinki, Finland
Institute of Prion Diseases and MRC Prion Unit, University College London, London, UK
Centre for Public Health, Queens University Belfast, Belfast, UK
Kiel Pain and Headache Center, Kiel, Germany
Department of Public Health, University of Helsinki, Helsinki, Finland
Human Genetics, School of Life Sciences, University of Nottingham, Nottingham UK
Hunter New England Local Health District, Newcastle, Australia
Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany
Institute of Human Genetics, School of Medicine, University of Bonn & University Hospital Bonn, Bonn, Germany
Department of Neurodegeneration, UCL Institute of Neurology, London, UK
Department of Neurology, Jagiellonian University Medical College, Kraków, Poland
QIMR Berghofer Medical Research Institute, Brisbane, Australia
Institute of Psychiatry Psychology and Neuroscience, Kings College London, UK
Human Genomics Research Group, Department of Biomedicine, University of Basel, Basel, Switzerland
Quantinuum Research LLC, San Diego, CA, USA
Department of Psychiatry and Psychotherapy, Friedrich-Alexander-Universität Erlangen-Nürnberg University Hospital, Erlangen, Germany
Department of Psychiatry and Global Brain Health Institute, Trinity College, Dublin, Ireland
University of Newcastle, Callaghan, Australia
Department of Adolescent Psychiatry, Helsinki University Central Hospital, Helsinki, Finland
Center for Neurobehavioral Genetics, Semel Institute for Neuroscience & Human Behavior, University of California at Los Angeles, Los Angeles, CA, USA
School of Psychiatry, University of New South Wales, Sydney, Australia
Black Dog Institute, Sydney, Australia
Sorbonne Université, Faculty of Médecine, Paris, France
Division of Psychiatry, Molecular Psychiatry Laboratory,University College London, London, UK
Maurice Wohl Clinical Neuroscience Institute, Department of Basic and Clinical Neuroscience, King's College London, London, UK
King's College Hospital, London, UK
Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA
Fundació ACE, Institut Català de Neurociències Aplicades, Barcelona, Spain and Universitat Internacional de Catalunya, Barcelona, Spain
Department of Psychiatry & Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands
Facultat de Medicina i Ciències de la Salut, Universitat Internacional de Catalunya (UIC), Barcelona, Spain
Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio, Texas, USA
Neurology and Neurogenetics Core, Framingham Heart Study, Framingham, MA, USA
School of Medicine, Boston University, Boston, MA, USA
School of Public Health, Boston University, Boston, MA, USA
Reference center for Gilles de la Tourette syndrome, Pitie-Salpetriere Hospital, Paris, France
Framingham Heart Study, Framingham, MA, USA
Center of Mental Health, Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, University Hospital of Wuerzburg, Wuerzburg, Germany
Department of Biostatistics, University of Washington, Seattle, WA, USA
Department of Psychiatry, University of Michigan, Ann Arbor, MI, USA
University of California, San Francisco, CA, USA
Cooper Medical School of Rowan University, Camden, NJ, USA
Thomas Jefferson University Hospital, Philadelphia, PA, USA
Children's Hospital of Philadelphia, Philadelphia, PA, USA
University of Chicago, Chicago, IL, USA
Department of Epidemiology, Erasmus Medical Centre, Rotterdam, the Netherlands
Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands
Department of Physiology, Saint Antoine Hospital, Paris, France
Center for Translational & Computational Neuroimmunology, Columbia University Medical Center, New York, NY, USA
Neurogenetics Program, Departments of Neurology and Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
Center For Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA
National Institute for Health and Welfare, Helsinki, Finland
Institute for Precision Health, University of California, Los Angeles, Los Angeles, CA, USA
Department of Psychiatry, Saarland University Hospital, Homburg, Germany
Institute of Social Medicine, Occupational Health and Public Health (ISAP), University of Leipzig, Leipzig, Germany
Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA
Department of Neurology II, Kepler University Clinic, Johannes Kepler University, Linz, Austria
Centre National Maladie 'Syndrome Rare Gilles de la Tourette', Groupe Hospitalier Pitié-Salpêtrière, Paris, France
Assistance Publique-Hôpitaux de Paris, Départment de Neurologie, Groupe Hospitalier Pitié-Salpêtrière, Paris, France
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Sorbonne Universités, UPMC Université Paris 06, UMR S 1127, CNRS UMR 7225, ICM, Paris, France
School of Psychology, Cardiff University, UK
Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA
Universitat Autònoma de Barcelona, Barcelona, Spain
Programa Corporatiu "Neurodevelopment Disorders along Life Span", Institut Català de la Salut, Barcelona, Spain
Clinica Galatea y PAIMM, Mental Health Program for Impaired Physicians, Barcelona, Spain
Washington University School of Medicine, St. Louis, MO, USA
Communication and Research Unit for Musculoskeletal Disorders (FORMI), Oslo University Hospital, Oslo, Norway
Department of Neurology, Oslo University Hospital, Oslo, Norway
Epilepsy Society, Chalfont-St-Peter, Bucks, UK
Harvard Medical School/McLean Hospital, Belmont, MA, USA
Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden
Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia
Department of Psychiatry, University of Helsinki, Helsinki, Finland
Illumina Inc., San Diego, CA, USA
Department of Psychiatry, University of California, San Francisco, San Francisco, CA, USA
Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA
23andMe Inc., Mountain View, CA, US
Institute of Public Health, Charité - Universitätsmedizin Berlin, Berlin, Germany
Central Institute of Mental Health, Department of Genetic Epidemiology in Psychiatry, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
Gertrude H. Sergievsky Center and Dept of Neurology, Columbia University, New York, NY, USA
Institute for Stroke and Dementia Research, Klinikum der Universitaet Muenchen, Munich, Germany
Department of Neurology and Epileptology, Hertie Institute for Clinical Brain Research, University of Tuebingen, Tuebingen, Germany
Butler Hospital, Providence, RI, USA
Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
Department of Neuroscience, Karolinska Institutet, Stockholm, Sweden
Institute of Human Genetics, University of Ulm, Ulm, Germany
Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Centre de Recherche du Centre Hospitalier de l'Universite de Montreal and Department of Neurosciences, Université de Montréal, Montréal, Canada
Department of Radiology and Nuclear Medicine, Erasmus Medical Centre, Rotterdam, the Netherlands
Department of Clinical Chemistry, Fimlab Laboratories and Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland
Department of Ophthalmology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
Washington University, St. Louis, MO, USA
National Centre for Register-based Research, Aarhus University, Aarhus, Denmark
Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark
Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain
Alpert Medical School of Brown University, Providence, RI, USA
Hospital of Telemark, Kragerø, Norway
Brigham and Women's Hospital, Boston, MA
Department of Neurology, University Hospital Essen, Germany
Neurogenetics Group, VIB-CMN, Antwerp, Belgium
University of Antwerp, Antwerp, Belgium
Department of Neurology, Antwerp University Hospital, Antwerp, Belgium
Department of Neurology, Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium
Bioinformatics Interdepartmental Program, University of California, Los Angeles, Los Angeles, CA, USA
Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
Department of Psychiatry, Psychosomatics and Psychotherapy, Center of Mental Health, University Hospital Wuerzburg, Wuerzburg, Germany
Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, USA
Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany
Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
INSERM U1061 - Neuropsychiatry: Epidemiological and Clinical Research, Montpellier, France
University of Montpellier, Montpellier, France
Memory Research and Resources Center, Department of Neurology, Montpellier University Hospital Gui de Chauliac, Montpellier, France
Norwegian Institute of Public Health, Oslo, Norway
University of Oslo, Oslo, Norway
Department of Biomedical Sciences, Cooper Medical School of Rowan University, Camden, NJ, USA
Department of Psychiatry, Center for Neurobiology and Behavior, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
Department of Biomedicine, Aarhus University, Aarhus, Denmark
NYU School of Medicine, New York, NY, USA
Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen, Essen, Germany
Amplexa Genetics A/S, Odense, Denmark
Department of Biomedicine and Human Genetics, Aarhus University, Aarhus, Denmark
Center for Integrative Sequencing (iSEQ), Aarhus University, Aarhus, Denmark
Aarhus Genome Center, Aarhus, Denmark
Institute of Mental Health, University of Nottingham, Nottingham, UK
Epilepsy Center/Neurocenter, Kuopio University Hospital, Kuopio, Finland
Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland
Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden
University of Edinburgh, Edinburgh, UK
Department of Epileptology, University Bonn Medical Center, Bonn, Germany
Institute of Experimental Epileptology and Cognition Research, University Bonn Medical Center, Bonn, Germany
INSERM, U 1127, CNRS UMR 7225, Sorbonne Universités, UPMC Univ Paris 06 UMR S 1127, Paris, France
Department of Clinical and Experimental Epilepsy, NIHR University College London Hospitals Biomedical Research Centre, UCL Institute of Neurology, London
Department of Genetics, University Medical Center Utrecht, the Netherlands
Epilepsy Foundation in the Netherlands (SEIN), Heemstede, the Netherlands
Departments of Pediatrics and Neurology, Ohio State University, Columbus, OH, USA
Nationwide Children's Hospital, Columbus, OH, USA
Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", University of Salerno,Italy
Boston University School of Medicine, Boston, MA, USA
Department of Biology, Brigham Young University, Provo, UT, USA
INSERM, UMR 1219, Bordeaux, France
University of Bordeaux, Bordeaux, France
Department of Neurology, University of California, San Francisco, CA, USA
IGBMC, CNRS UMR 7104/INSERM U964/Université de Strasbourg, Illkirch, France
National Alzheimer Coordinating Center (NACC), Department of Epidemiology, University of Washington, Seattle, WA, USA
De Bascule, Amsterdam, The Netherlands
Department of Child and Adolescent Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Department of Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands
Centre for Neuroimaging and Cognitive Genomics (NICOG), National University of Ireland, Galway, Galway, Ireland
Danish Epilepsy Centre, Filadelfia, Dianalund, Denmark
Institute for Regional Health Services, University of Southern Denmark, Odense, Denmark
Trinity College Dublin, Dublin, Ireland
United Christian Hospital, Hong Kong
Hong Kong Sanatorium and Hospital, Hong Kong
Vanderbilt University Medical Center, Nashville, TN, USA
Epilepsy Research Centre, University of Melbourne, Austin Health, Heidelberg, Australia
Department of Neurology, University of Cincinnati, Cincinnati, OH, USA
UC Gardner Neuroscience Institute, Cincinnati, OH, USA
Department of Neurology, Duke University School of Medicine, Durham, NC, USA
NCBES Galway Neuroscience Centre, National University of Ireland, Galway, Galway, Ireland
Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany
Eating Disorders Unit, Department of Child and Adolescent Psychiatry, Medical University of Vienna, Vienna, Austria
Department of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USA
Division of Life Science, Hong Kong University of Science and Technology, Hong Kong Special Administrative Region, China
Rouen University Hospital, Rouen, France
Inserm U1245, Rouen, France
Child and Adolescent Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
Department of Neurology, Inselspital, Bern University Hospital, University of Bern, Switzerland
Department of Neurology, University of Munich Hospital, Grosshadern, University of Munich, Germany
Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Department of Psychiatry, Royal College of Surgeons in Ireland, Dublin, Ireland
Department of Paediatrics, Royal Children's Hospital, The University of Melbourne, Melbourne, Victoria, Australia
Institute of Neuropathology, Bonn University Medical School, Bonn, Germany
Chalfont Centre for Epilepsy, Bucks, UK
University Hospital of Wales, Cardiff, UK
Institute of Neuroscience, Newcastle University, Newcastle, UK
Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway
Division of Clinical Neuroscience, Oslo University Hospital and University of Oslo, Oslo, Norway
Pediatric Neurology and Muscular Diseases Unit-Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health University of Genoa, "G. Gaslini" Institute, Genova, Italy
Department of Epileptology, University Hospital Bonn, Bonn, Germany
Child and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, Brazil
Section of Epileptology, Department of Neurology, University Hospital RWTH Aachen, Aachen, Germany
Center for Integrative Genomics, University of LaUSAnne, LaUSAnne, Switzerland
Department of Psychology, Emory University, Atlanta, GA, USA
Institute of Applied Health Research, University of Birmingham, UK
Department of Neurology, Admiraal De Ruyter Hospital, Goes, The Netherlands
Centre National de Recherche en Génomique Humaine (CNRGH), Institut de biologie François Jacob, CEA, Evry, France
Laboratory of Neurogenetics, G. Gaslini Institute, Genova, Italy
Department of Psychiatry, Dalhousie University, Halifax, Canada
Escuela de Ciencias de la Salud, Universidad Pontificia Bolivariana, Medellín, Colombia
National Institute of Mental Health, Klecany, Czech Republic
Department of Neurology, College of Medicine-Jacksonville, University of Florida, Jacksonville, FL, USA
Boston VA Research Institute, Boston, MA, USA
Brigham Women's Hospital Division of Aging, Harvard Medical School, Boston, MA, USA
Institute for Genomic Medicine, Columbia University Medical Center, New York, NY, USA
University of Liverpool, Liverpool, UK
Walton Centre NHS Foundation Trust, Liverpool, UK
Department of Neurology and Epileptology, University Hospital Tuebingen, Tuebingen, Germany
Department of Neurology, University of Ulm, Ulm, Germany
CWZ Hospital, Nijmegen, Netherlands
Department of Neurology, Medical University of Vienna, Austria
Laboratorio de Genética Molecular, SIU, Universidad de Antioquia, Medellín, Colombia
Philipps-Universität Marburg and Marburg University Hospital UKGM, Marburg, Germany
INSERM U1167 LabEx DISTALZ, Lille, France
Institut Pasteur de Lille, U1167, Lille, France
Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France
Kartini Clinic, Portland, OR, USA
Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany
German Center for Neurodegenerative Diseases (DZNE), Tübingen, Germany
Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
Montreal Neurological Institute, McGill University, Montréal, Canada
Department of Neurology and Neurosurgery, McGill University, Montréal, Canada
Department of Gerontology, Hôpital Broca, AH-HP, Paris, France
Department of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany
Avera Institute for Human Genetics, Sioux Falls, SD, USA
Hôpital Paul Brousse Université Paris Sud XI, Le Kremlin-Bicêtre, Paris, France
INSERM U1220, IRSD, Toulouse, France
Université Paul Sabatier, Toulouse, France
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
MRC Integrative Epidemiology Unit and Bristol Medical School, University of Bristol, Bristol, UK
Zorg op Orde BV, Leidschendam, The Netherlands
Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland
Department of Medical Informatics and Clinical Epidemiology, Oregon Health & Science University, Portland, OR, USA
Division of Psychological & Social Medicine and Developmental Neurosciences, Faculty of Medicine, Technischen Universität Dresden, Dresden, Germany
Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA, USA
Department of Child & Adolescent Psychiatry & Psychosomatic Medicine of University Clinics, RWTH Aachen, Aachen, Germany
Analytic Translational Genetics Unit, Massachusetts General Hospital Harvard Medical School, Boston, Massachusetts, USA
Carver College of Medicine, University of Iowa, Iowa City, IA, USA
Translational Genomics Research Institute, Neurogenomics Division, Phoenix, AZ, USA
Department of Psychiatry, McGill University, Montréal, Canada
Altrecht Eating Disorders Rintveld, Altrecht Mental Health Institute, Zeist, The Netherlands
Faculty of Social Sciences, University of Utrecht, Utrecht, the Netherlands
Medical Genetics Unit, Department SDB, University of Padova, Padova, Italy
UOC Genetica ed Epidemiologica Clinica Az. Ospedaliera, Padova, Italy
Department of Human Genetics, CHU Sart-Tilman, University of Liège, Liège, Belgium
Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands
Department of Rheumatology, CHU Sart-Tilman, University of Liège, Liège, Belgium
Department of Cancer Epidemiology and Prevention, Cancer Center and M. Sklodowska-Curie Institute of Oncology, Warsaw, Poland
Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
Department of Psychiatry, University of Medical Sciences, Poznan, Poland
Department of Psychiatry, University of Perugia, Perugia, Italy
Department of Psychological and Brain Sciences, University of Iowa, Iowa City, IA, USA
Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
Department of Mental and Physical Health and Preventive Medicine, University of Campania "luigi Vanvitelli", Naples, Italy
Pediatric Neurology Research Group, Vall d'Hebron Research Institute, Autonomous University of Barcelona, Barcelona, Spain
Eating Disorders Unit, 1st Psychiatric Department, National and Kapodistrian University of Athens, Athens, Greece
Maastricht University Medical Centre, Maastricht, the Netherlands
Aglaia Kyriakou Childrens Hospital, Athens, Greece
University of Pittsburgh, Pittsburgh, PA, USA
Eating Disorders Unit, Department of Psychiatry, First Faculty of Medicine, Charles University, Prague, Czech Republic
Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
General University Hospital, Prague, Czech Republic
Medical University of Vienna, Austria
School of Psychology, Flinders University, Adelaide, Australia
Vall d'Hebron Research Institute, Barcelona, Spain
Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, CA, USA
Institut de Recerca Sant Joan de Déu, Barcelona, Spain
Department of Psychosis Studies, Institute of Psychiatry, King's College London, London, UK
Institut de Biomedicina de la Universitat de Barcelona (IBUB), Barcelona, Spain
Department of Genetics, Microbiology & Statistics, Faculty of Biology, University of Barcelona, Barcelona, Spain
Centre for Genomic Regulation (CRG), Barcelona, Spain
Departamento de Genética, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
ADHD Outpatient Clinic, Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil
Departments of Psychology and Human & Molecular Genetics, College Behavioral and Emotional Health Institute, Virginia Commonwealth University, Richmond, Virginia
Child and Adolescent Mental Health Unit, Hospital Universitario Mútua de Terrassa, Barcelona, Spain
Broad Institute of MIT and Harvard, Cambridge, USA
NORMENT, Div. of Mental Health and Addiction, University of Oslo, Oslo, Norway
Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, the Netherlands
Oslo University Hospital, Oslo, Norway
Department of Psychology, University of Oslo, Norway
K. G. Jebsen Centre for Research on Neuropsychiatric Disorders, University of Bergen, Bergen, Norway
Department of Biological and Medical Psychology, University of Bergen, Bergen, Norway
Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA
Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
Department of Medicine, University of Washington, WA, USA
MRC Unit on Risk & Resilience in Mental Disorders, Department of Psychiatry, University of Cape Town, Cape Town, South Africa
NORMENT, K.G. Jebsen Center for Psychosis Research, Department of Clinical Science, University of Bergen, Norway
Department of Medical Genetics, Haukeland University Hospital, Bergen, Norway
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne & Melbourne Health, Victoria, Australia
Department of Genetics and Genomic Sciences, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA
The Mindich Child Health & Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
McLaughlin Centre and Department of Molecular Genetics, University of Toronto, Toronto, Canada
The Centre for Applied Genomics, Hospital for Sick Children, Toronto, Canada
Neurosciences and Mental Health Program, Research Institute, Hospital for Sick Children, Toronto, Canada
University of Toronto, Toronto, Canada
UK Dementia Research Institute, University College London, London, UK
UMC Utrecht, Utrecht, The Netherlands
Biopsychosocial Corporation, Vienna, Austria
Department of Psychiatry and Psychotherapy, Medical University of Vienna, Vienna, Austria
Centre for Neural Engineering, Department of Electrical and Electronic Engineering, University of Melbourne, Victoria, Australia
Zentren für Seelische Gesundheit, BBRZ-Med, Vienna, Austria
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
Rheumatology Unit, Department of Medicine, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
Weill Cornell Medical College, New York, New York, USA
School of Medicine, University of North Dakota, Grand Forks, ND, USA
Neuropsychiatric Research Institute, Fargo, ND, USA
Department of Molecular Neuroscience, Institute of Neurology, University College London, London, UK
Department of Psychiatry & Biobehavioral Sciences, Semel Institute for Neuroscience & Human Behavior, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
BioRealm, Walnut, California, USA
Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA
Oregon Research Institute, Eugene, OR, USA
Landspitali National University Hospital, Reykjavik, Iceland
Hospital for Sick Children, Toronto, Canada
Centro de Investigación Biomédica en Red de Enfermedades Raras (CIBERER), Instituto de Salud Carlos III, Madrid, Spain
Department of Psychiatry and Human Behavior, University of California, Irvine, Irvine, CA, USA
Department of Medicine, Harvard Medical School, Boston, MA, USA
Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
Department of Psychiatry, University of California, Los Angeles, Los Angeles, CA, USA
Department of Psychiatry and Behavioral Science, Stanford University, Stanford, California, USA
Department of Psychiatry, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
The Florey Institute of Neuroscience and Mental Health, Melbourne, Victoria, Australia
Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands
Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK
SUNY Downstate Medical Center, Brooklyn, NY, USA
Department of Medicine, Boston University School of Medicine, Boston, MA, USA
Sección de Neuropediatría, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy
Department of Psychiatry, University of British Columbia, Vancouver, Canada
Institute of Mental Health, University of British Columbia, Vancouver, Canada
Institute for Human Genetics, University of California, San Francisco, San Francisco, CA, USA
Cardiff University, Medical Research Council Center for Neuropsychiatric Genetics & Genomics, Institute of Psychology, Medicine & Clinical Neuroscience, Cardiff, UK
Center for Applied Genomics of The Children's Hospital of Philadelphia, Philadelphia, PA, USA
Stella Maris Clinical Research Institute for Child and Adolescent Neuropsychiatry, Pisa, Italy
Sorbonne Université, INSERM, CNRS, Neuroscience Paris Seine, Institut de Biologie Paris Seine, Paris, France
Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK
NIHR Biomedical Research Centre in Mental Health Maudsley Hospital, London, UK
University College London, London, UK
LifeOmic, Indianapolis, IN, USA
Instituto Nacional de Saúde Doutor Ricardo Jorge, Lisboa, Portugal
Biosystems and Integrative Sciences Institute - BioISI, University of Lisboa, Lisboa, Portugal
Department of Psychiatry and Behavioral Sciences, Duke University, Durham, NC, USA
Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA
Dementia Research Institute, Cardiff University, Cardiff, UK
Max Planck Institute of Psychiatry, Munich, Germany
Institute of Translational Medicine, University of Liverpool, Liverpool, UK
Rush Alzheimers Disease Center, Chicago, IL, USA
Department of Neurological Sciences, Rush Medical College, Chicago, IL, USA
Department of Behavioral Sciences, Rush Medical College, Chicago, IL, USA
Child Developmental Center, Hospital Pediátrico, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal
University Clinic of Pediatrics, Faculty of Medicine, University of Coimbra, Coimbra, Portugal
Dept of Clinical Genetics, Our Lady's Children's Hospital, Crumlin, Dublin, Ireland
School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
Department of Pediatrics, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Division of Molecular Genome Analysis and Division of Cancer Genome Research, German Cancer Research Center (DKFZ), Heidelberg, Germany
Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA
Inserm U955, Psychiatrie Translationnelle, Créteil, France
Faculté de Médecine, Université Paris Est, Créteil, France
Fondation FondaMental, Créteil, France
Children's Hospital Los Angeles, Los Angeles, CA, USA
Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
Cognitive Genetics and Cognitive Therapy Group, Neuroimaging, Cognition and Genomics (NICOG) Centre, School of Psychology and Discipline of Biochemistry, National University of Ireland Galway, Galway, Ireland
Faculty of Health and Medicine, University of Newcastle, Callaghan, Australia
Yale Center for Genome Analysis, Yale University, New Haven, CT, USA
College of Medicine, University of Kentucky, Lexington, KY, USA
Department of Genetics, Yale University School of Medicine, New Haven, CT, USA
Division of Child and Adolescent Psychiatry, Department of Psychiatry and Human Behavior, Brown University, Providence, RI, USA
Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK
Northumberland, Tyne & Wear NHS Foundation Trust, Northumberland, UK
Genomics Medicine Ireland, Dublin, Ireland
Institute of Clinical Molecular Biology, Kiel University and University Hospital Schleswig-Holstein, Kiel, Germany
Clinic of Internal Medicine I, University Hospital Schleswig-Holstein, Kiel, Germany
Banner Sun Health Research Institute, Sun City, AZ, USA
Department of Psychiatry, Hospital for Sick Children and University of Toronto, Toronto, Canada
Oxford Health NHS Foundation Trust, Oxford, UK
Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Canada
Hospital for Psychiatry and Psychotherapy, Cologne, Germany
Department of Neurology, University of Florida, Gainesville, FL, USA
Harvard Medical School, Boston, MA, USA
Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, IA, USA
Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA
Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA
Center for Psychiatric Research, Maine Medical Center Research Institute, Portland, ME, USA
Department of Psychiatry, Tufts University School of Medicine, Boston, MA, USA
Child and Adolescent Psychiatry Department, Robert Debre Hospital, APHP, Paris, France
Department of Psychiatry, University of Oxford, Oxford, UK
Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France
Centre d'Etudes et de Recherches en Psychopathologie et Psychologie de la Santé (CERPPS), Université Toulouse Jean Jaurès, Toulouse, France
CERESA, Toulouse, France
Institut Universitaire de France, Paris, France
Department of Neurology, Brigham & Women's Hospital, Harvard Medical School, Boston, MA, USA
Academic Centre on Rare Diseases University College Dublin (ACoRD/UCD), Dublin, Ireland
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Centre for Genetic Epidemiology, Institute for Clinical Epidemiology and Applied Biometery, University of Tubingen, Germany
Layton Aging & Alzheimer's Disease Center, Oregon Health & Science University, Portland, OR, USA
Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany
Department of Psychiatry and Behavioral Sciences, NorthShore University HealthSystem Research Institute, Evanston, IL, USA
Department of Psychiatry and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA
Human Genetics Branch, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD, USA
Department of Pathology, Duke University School of Medicine, Durham, NC, USA
Molecular and Behavioral Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA
Charite Universitatsmedizin Berlin, Berlin, Germany
Division of Neurocritical Care and Emergency Neurology, Massachusetts General Hospital, Boston, MA, USA
SRH University Heidelberg, Academy for Psychotherapy, Heidelberg, Germany
Laboratory of Psychiatric Genetics, Department of Psychiatry, Poznan University of Medical Sciences, Poznan, Poland
Douglas Mental Health University Institute, McGill University, Montreal, Canada
Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Department of Translational Research in Psychiatry, Max-Planck Institute of Psychiatry, Munich, Germany
National Centre for Mental Health, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK
Fundació Docència i Recerca Mútua Terrassa
Yulius Academy, Yulius Mental Health Organization, Barendrecht, The Netherlands
Department Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, VU University, Amsterdam, The Netherlands
Department Clinical Genetics, VU University Medical Center, Amsterdam Neuroscience, Amsterdam, The Netherlands
School of Biomedical Sciences and Pharmacy, The University of Newcastle, Callaghan, Australia
Headache Unit, Neurology Department, Hospital Vall d'Hebron, Barcelona, Spain
Headache Research Group, VHIR, Autonomous University of Barcelona, Barcelona, Spain
Austin Health, Heidelberg, Victoria, Australia
University of Split School of Medicine, Split, Croatia
Department of Neurology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
Department of Psychiatry (UPK), University of Basel, Basel, Switzerland
Discipline of Psychiatry, University of Adelaide, Adelaide, Australia
Bela Menso Brain and Behaviour Centre, James Cook University, Varsity Lakes, Australia
Bond University, Faculty of Society and Design, Robina, Australia
Queensland Brain Institute, University of Queensland, Brisbane, Australia
Division of Psychiatry, Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK
Priority Research Centre for Brain and Mental Health Research, Hunter Medical Research Institute, Newcastle, Australia
Lou Ruvo Center for Brain Health, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA
Department of Psychology, University of Denver, Denver, CO, USA
University Health Network, University of Toronto, Toronto, Canada
K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Biomedicine, University of Bergen, Norway
Division of Psychiatry, Haukeland University Hospital, Bergen, Norway
Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK
Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany
Department of Biochemistry and Molecular Biology II, Institute of Neurosciences, Center for Biomedical Research, University of Granada, Granada, Spain
University of Virginia Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA
Institute of Biological Psychiatry, Roskilde, Denmark
Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark
Schizophrenia Research Institute, Sydney, Australia
Child Health Research Centre, University of Queensland, Brisbane, Australia
University of Groningen, Groningen, the Netherlands
Child and Youth Mental Health Service, Children's Health Queensland Health and Hospital Service, Brisbane, Australia
Brain and Mind Centre, University of Sydney, Sydney, Australia
School of Psychology and Counselling, Faculty of Health, Institute of Health and Biomedical Innovation, Queensland University of Technology, Queensland, Australia
University of Queensland, Brisbane, Australia
Faculdade de Medicina FMUSP, Universidade de São Paulo, São Paulo, Brazil
Amsterdam Public Health Research Institute, VU Medical Center, Amsterdam, the Netherlands
Department of Research and Innovation, GGZ Ingeest, Specialized Mental Health Care, Amsterdam, the Netherlands
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK
Department of Psychiatry, Harvard Medical School, Boston, MA, USA
Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA
Department of Child and Adolescent Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Department of Neurology, School of Medicine, Emory University, Atlanta, GA, USA
Janssen Research & Development LLC, Titusville, NJ, USA
Dept of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD, USA
Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany
German Centre for Cardiovascular Research (DZHK e.V.), Partner Site Greifswald, Greifswald, Germany
Department of Clinical Sciences, University of Copenhagen, Copenhagen, Denmark
Research School of Behavioural and Cognitive Neurosciences, Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands
Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain
Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
Faculty of Science, Medicine and Health, University of Wollongong, Wollongong, Australia
Institute of Mental Health, Singapore, Singapore
Department of Psychiatry GGZ INGEEST, Amsterdam, the Netherlands
Department of Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY, USA
Mathison Centre for Mental Health Research & Education, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada
Departments of Psychiatry and Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Canada
Krembil Research Institute, University Health Network, Toronto, Canada
Grupo de Genética Molecular, Instituto de Biología, Facultad de Ciencias Exactas y Naturales, Universidad de Antioquia, Medellín, Colombia
Johns Hopkins University School of Medicine, Baltimore, MD, USA
Centre for Prevention of Stroke and Dementia, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK
Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA
Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Assistance Publique - Hopitaux de Paris, GH Pitié-Salpêtrière, Paris, France
Depto. Farmacogenética, Instituto Nacional de Psiquiatria Ramon de la Fuente Muñiz, Mexico City, Mexico
Centre Hosp. Univ Lille, Lille, France
Department of Psychiatry, Sao Paulo Medical School, University of Sao Paulo, Sao Paulo, Brazil
K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Clinical Science, University of Bergen, Norway
Department of Psychiatry, University of Groningen and University Medical Center, Groningen, the Netherlands
Department of Specialized Trainings, GGZ Drenthe Mental Health Care Services, Assen, the Netherlands
National Institute of Genomic Medicine (INMEGEN), Ciudad de México, Mexico
Clinical Research, Grupo Médico Carracci, Mexico City, Mexico
Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore
Department of Neurology, Oregon Health and Science University, Portland, OR, USA
Department of Neurology and Parkinson's Disease Research Education and Clinical Care Center (PADRECC), Portland Veterans Affairs Medical Center, Portland, OR, USA
Sorbonne Université, CNRS UMR 7222 Institut des Systèmes Intelligents et Robotiques, Paris, France
Departments of Neurology and Neurosurgery, University of Florida, Gainesville, FL, USA
Fixel Center for Neurological Diseases, University of Florida, Gainesville, FL, USA
Division of Psychiatry, University of Edinburgh, Edinburgh, UK
Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Child and Adolescent Psychiatry/Psychotherapy, University Medical Center, Goettingen, Germany
Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA
Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany
Statistical and Genomic Epidemiology Laboratory, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia
Department of Computer Science, New Jersey Institute of Technology, New Jersey, USA
Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada
Department of Psychiatry, University of California San Diego, La Jolla, CA, USA
Departments of Medicine and Psychiatry, School of Medicine University of Cantabria-IDIVAL, University Hospital Marqués de Valdecilla, Santander, Spain
University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Department of Human Genetics, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA
University of Lincoln, Lincoln, UK
Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain
Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands
Department of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands
Neuroscience Research Australia, Sydney, Australia
Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands
Minerva Neurosciences Inc., Waltham, MA, USA
Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
VA Boston Healthcare System, Boston, MA, USA
Netherlands Twin Register, Vrije Universiteit, Amsterdam, the Netherlands
Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland
Department of Biomedicine, University of Basel, Basel, Switzerland
Ospedale San Raffaele, Milano, Italy
Columbia University, New York, NY, USA
School of Medical Sciences, University of New South Wales, Sydney, Australia
APC Microbiome Ireland, University College Cork, Cork, Ireland
Department of Psychiatry, University College Cork, Cork, Ireland
Neuroimaging, Cognition and Genomics (NICOG) Centre, School of Psychology, National University of Ireland Galway, Galway, Ireland
Icahn School of Medicine at Mount Sinai, New York, NY, USA
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Seaver Autism Center for Research and Treatment, Icahn School of Medicine at Mount Sinai, New York, NY, USA
Center for Psychiatric Genetics, NorthShore University HealthSystem Research Institute, Evanston, IL, USA
Department of Psychiatry and Behavioral Neuroscience, University of Chicago, Chicago, IL, USA
Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands
Arkin, Amsterdam, the Netherlands
School of Biomedical Sciences, Chinese University of Hong Kong, Shatin, Hong Kong
Department of Pathology, University of Utah, Salt Lake City, UT, USA
Department of Pathology, University of Washington, Seattle, WA, USA
Department of Cognitive Neuroscience, Donders Institute for Brain, Cognition and Behavior, Radboud University Medical Centre, Nijmegen, The Netherlands
Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
Department of Medical Genetics, Medical University, Sofia, Bulgaria
Bio4Dreams Srl, Milan, Italy
Department of Cerebrovascular Diseases, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy
PhD Program in Neuroscience, University Milano-Bicocca, Monza, Italy
Department of Molecular Bases of Human Genetics, Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia
KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research of Common Diseases, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
Latvian Biomedical Research and Study Centre, Riga, Latvia
Massachusetts General Hospital, Boston, MA, USA
Youthdale Treatment Centers, Toronto, Canada
Chinese University of Hong Kong, Hong Kong
Sheba Medical Center, Ramat Gan, Israel
Departments of Psychiatry and Genetics, Washington University School of Medicine, St. Louis, MO, USA
UCL Genetics Institute, University College London, London, UK
Centre for Psychiatry, Barts and the London School of Medicine and Dentistry, London, UK
Institute of Cardiovascular Research, Royal Holloway University of London, London, UK
Ashford & St Peters NHS Foundation Trust, Surrey, UK
School of Medicine & Public Health, University of Newcastle, Callaghan, Australia
Priority Research Centre for Health Behaviour, University of Newcastle, Callaghan, Australia
Hunter Medical Research Institute, Newcastle, Australia
Groote Schuur Hospital, Cape Town, South Africa
Wellcome Centre for Human Genetics, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Oxford Centre for Diabetes, Endocrinology and Metabolism, Nuffield Department of Medicine, University of Oxford, Oxford, UK
Department of Human Genetics, Wellcome Sanger Institute, Hinxton, Cambridgeshire, UK
NORMENT, K.G. Jebsen Centre for Psychosis Research, Institute of Clinical Medicine, University of Oslo, Oslo, Norway
Research Unit, Sørlandet Hospital, Kristiansand, Norway
Unidad de Salud Mental, Hospital Regional Universitario de Malaga, Malaga, Spain
Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA
Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt am Main, Germany
Department of Statistics and Applied Probability, University of California, Santa Barbara, CA, USA
Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece
Computational Research Division, Lawrence Berkeley National Laboratory, University of California at Berkeley, Berkeley, CA, USA
Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
NSW Health Pathology, Newcastle, Australia
Yale University School of Medicine, New Haven, CT, USA
Virginia Institute for Psychiatric and Behavioral Genetics, Department of Psychiatry, Virginia Commonwealth University, Richmond, VA, USA
Institute of Psychiatry, Psychology & Neuroscience, Social Genetics & Developmental Psychiatry Center, MRC, Kings College London, London, UK
NIHR Maudsley Biomedical Research Centre, South London & Maudsley NHS Trust & King's College London, London, UK
Departments of Psychiatry and Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, MA, USA
Munich Cluster for Systems Neurology (SyNergy), Munich, Germany
Issue Date: 22-Jun-2018
Citation: Science (New York, N.Y.) 2018; 360(6395): eaap8757
Abstract: Disorders of the brain can exhibit considerable epidemiological comorbidity and often share symptoms, provoking debate about their etiologic overlap. We quantified the genetic sharing of 25 brain disorders from genome-wide association studies of 265,218 patients and 784,643 control participants and assessed their relationship to 17 phenotypes from 1,191,588 individuals. Psychiatric disorders share common variant risk, whereas neurological disorders appear more distinct from one another and from the psychiatric disorders. We also identified significant sharing between disorders and a number of brain phenotypes, including cognitive measures. Further, we conducted simulations to explore how statistical power, diagnostic misclassification, and phenotypic heterogeneity affect genetic correlations. These results highlight the importance of common genetic variation as a risk factor for brain disorders and the value of heritability-based methods in understanding their etiology.
URI: http://ahro.austin.org.au/austinjspui/handle/1/18152
DOI: 10.1126/science.aap8757
ORCID: 0000-0002-0073-4675
0000-0003-3864-9828
0000-0001-8422-6530
0000-0003-1131-661X
0000-0003-1784-5483
0000-0002-6407-0302
0000-0002-8908-6968
0000-0001-9212-2520
0000-0003-3622-835X
0000-0001-6059-4267
0000-0001-7901-4365
0000-0003-1770-3100
0000-0003-2053-1792
0000-0001-7772-3264
0000-0002-0949-8752
0000-0002-0654-387X
0000-0002-9217-3982
0000-0003-0870-9412
0000-0001-7749-182X
0000-0003-2208-7058
0000-0001-9715-4943
0000-0002-4069-0259
0000-0002-9500-3348
0000-0002-7772-5910
0000-0002-0381-6334
0000-0002-6619-873X
0000-0002-1014-9138
0000-0001-6717-4089
0000-0003-1513-6077
0000-0002-2311-2174
0000-0002-6614-8417
0000-0003-4580-841X
PubMed URL: 29930110
Type: Journal Article
Research Support, Non-U.S. Gov't
Research Support, N.I.H., Extramural
Appears in Collections:Journal articles

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