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|Title:||Xp11 translocation renal cell carcinoma paraneoplastic syndrome presenting as cutaneous vasculitis: first reported case of yet another mask.|
|Authors:||Pascoe, Claire;Christidis, Daniel;Clouston, David;Lawrentschuk, Nathan L|
|Affiliation:||Department of Urology, Austin Health, Heidelberg, Victoria, Australia|
YURO, Young Urology Researchers Organisation, Melbourne, VIC, Australia
Cancer Surgery, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia
Department of Pathology, Tissue Path, Mount Waverley, Victoria, Australia
|Citation:||BMJ case reports 2018; online first: 21 April|
|Abstract:||Renal cell carcinoma is historically known as the 'great masquerader' with 40% of patients experiencing a paraneoplastic syndrome. Translocation carcinoma represents one-third of renal cancer in paediatric patients but less than 3% of renal cancers in patients aged 18-45 years where the clinical course is often rapidly terminal. There are less than 10 reported cases of leucoclastic vasculitis associated with clear cell carcinoma reported in the literature and 10 case reports of translocation carcinoma in adults. To our knowledge, we present the first reported case of Xp11 translocation carcinoma presenting as cutaneous vasculitis, as part of a paraneoplastic syndrome, in an adult patient. Our case highlights that renal cell cancers are truly the 'great masquerader' and a rash can be the first sign of renal malignancy.|
|Appears in Collections:||Journal articles|
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