Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/17520
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dc.contributor.authorAncona, Paolo-
dc.contributor.authorBailey, Michael-
dc.contributor.authorBellomo, Rinaldo-
dc.date2018-01-29-
dc.date.accessioned2018-04-24T06:54:31Z-
dc.date.available2018-04-24T06:54:31Z-
dc.date.issued2018-01-29-
dc.identifier.citationJournal of critical care 2018; 45: 58-64-
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/17520-
dc.description.abstractTo describe characteristics, incidence and outcome of patients with Guillain-Barre syndrome (GBS) admitted to ICU. We conducted a binational, retrospective, observational, epidemiological study. We compared the baseline characteristics, physiological conditions and outcomes for GBS patients with or without mechanical ventilation (MV) and of survivors and non-survivors. We studied 711 patients admitted to 173 ICUs between 2005 and 2015. We found an increasing proportion of GBS admissions per year (P < 0.03). 237 patients required MV. These patients had higher APACHE III scores (47 vs 31), worse PaO2/FiO2 ratio (P/F 258 v 341), a significantly longer ICU LOS (25 v 4 days) (P < 0.0001, all comparisons) and a greater incidence of pre-ICU cardio-respiratory arrest (6.7% v 1.2%). Similarly, non-survivors were 5-times more likely to have experienced a pre-ICU cardio-respiratory arrest. Overall, ICU and hospital mortality were 3.9% and 6.9%, respectively and increased to 9.7% and 14.3% in the MV group. MV patients remained in hospital for almost 40 days. GBS represents a small but increasing proportion of ICU admissions with one-third of patients receiving MV. Overall in-hospital mortality is relatively low but doubles if MV is needed. These observations provide important prognostic information to clinicians involved in the care of these patients.-
dc.language.isoeng-
dc.subjectGuillain-Barre syndrome-
dc.subjectIntensive care-
dc.subjectMechanical ventilation-
dc.subjectMortality-
dc.subjectParalysis-
dc.subjectRespiratory arrest-
dc.titleCharacteristics, incidence and outcome of patients admitted to intensive care unit with Guillain-Barre syndrome in Australia and New Zealand.-
dc.typeJournal Article-
dc.identifier.journaltitleJournal of critical care-
dc.identifier.affiliationDepartment of Intensive Care, Austin Health, Heidelberg, Victoria, Australia-
dc.identifier.affiliationDepartment of Anaesthesiology and Intensive Care, Catholic University of Sacred Hearth, "A. Gemelli" University Hospital, Rome, Italy-
dc.identifier.affiliationAustralian and New Zealand Intensive Care Research Centre, Monash University School of Public Health and Preventive Medicine, Alfred Hospital, Melbourne, Victoria, Australia-
dc.identifier.doi10.1016/j.jcrc.2018.01.016-
dc.identifier.orcid0000-0002-1650-8939-
dc.identifier.pubmedid29413724-
Appears in Collections:Journal articles

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