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|Title:||Relationship between autonomic cardiovascular control and obstructive sleep apnoea in persons with spinal cord injury: a retrospective study.|
|Authors:||Fang, Xizhe;Goh, Min Yin;O'Callaghan, Christopher;Berlowitz, David J|
|Affiliation:||Institute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australia|
University of Melbourne, Melbourne, VIC Australia
Department of Clinical Pharmacology, Austin Health, Heidelberg, Victoria, Australia
The Spinal Research Institute, Melbourne, VIC Australia
|Citation:||Spinal cord series and cases 2018; 4: 29|
|Abstract:||Retrospective study. To determine if there is an association between obstructive sleep apnoea (OSA) and blood pressure (BP) pattern or heart rate variability (HRV) in people with spinal cord injury (SCI). A state-based spinal cord service in Victoria, Australia. We identified 42 subjects who had ambulatory BP monitoring (ABPM) within 6 months of a diagnostic sleep study at Austin Hospital between 2009 and 2014. Markers for autonomic function, including circadian BP pattern and HRV were extracted from the ABPM study database. Apnoea/hypopnoea index (AHI), arousals/hour and oxygen desaturation index were extracted from the sleep study database. Subjects with a nocturnal systolic BP dipping more than 10% of daytime value were defined as dippers, between 10 and 0% were non-dippers and those with a higher night than day systolic BP were reverse dippers. Severity of OSA is classified as non-OSA (AHI < 5), mild (AHI 5-15), moderate (AHI 15-30) and severe (AHI > 30). Subjects (n = 42) were predominantly male (85.7%), aged 44 ± 15.4 (mean ± SD), with a BMI of 24.4 ± 5.7 (mean ± SD) and mainly tetraplegic (92.9%). There was no difference in AHI, oxygen desaturation index or arousals/hour between dippers, non-dippers and reverse dippers. None of the HRV parameters differed between dippers, non-dippers and reverse dippers. No differences were found in 24 h, night-time, daytime or nocturnal dip in BP between subjects with non-OSA, mild, moderate and severe OSA. We found no relationship between BP pattern or HRV and the severity of OSA in persons with SCI.|
|Appears in Collections:||Journal articles|
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