Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/17188
Title: Does Fluid Type and Amount Affect Kidney Function in Critical Illness?
Authors: Glassford, Neil J;Bellomo, Rinaldo
Affiliation: Intensive Care Unit, Austin Health, Heidelberg, Victoria, Australia
Department of Epidemiology and Preventive Medicine, Monash University, Australian and New Zealand Intensive Care Research Centre, Melbourne, VIC 3004, Australia
School of Medicine, The University of Melbourne, VIC 3010, Australia
Issue Date: Apr-2018
EDate: 2018-02-03
Citation: Critical care clinics 2018; 34(2): 279-298
Abstract: Acute kidney injury (AKI) is common, although commonly used clinical diagnostic markers are imperfect. Intravenous fluid administration remains a cornerstone of therapy worldwide, but there is minimal evidence of efficacy for the use of fluid bolus therapy outside of specific circumstances, and emerging evidence associates fluid accumulation with worse renal outcomes and even increased mortality among critically ill patients. Artificial colloid solutions have been associated with harm, and chloride-rich solutions may adversely affect renal function. Large trials to provide guidance regarding the optimal fluid choices to prevent or ameliorate AKI, and promote renal recovery, are urgently required.
URI: http://ahro.austin.org.au/austinjspui/handle/1/17188
DOI: 10.1016/j.ccc.2017.12.006
PubMed URL: 29482907
Type: Journal Article
Review
Subjects: Acute kidney injury
Albumin
Balanced solution
Colloid
Crystalloid
Hydroxyethyl starch
Intravenous fluid therapy
Succinylated gelatin
Appears in Collections:Journal articles

Files in This Item:
There are no files associated with this item.


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.