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Title: Radiotherapy-related complications presenting to a urology department - a more common problem than previously thought?
Authors: Ma, J L;Hennessey, Derek B;Newell, Bradley P;Bolton, Damien M;Lawrentschuk, Nathan
Affiliation: Department of Urology, Austin Health, Heidelberg, Victoria, Australia.
Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, Victoria, Australia.
University of Melbourne, Victoria, Australia
Issue Date: 23-Jan-2018
EDate: 2018
Citation: BJU international 2018; online first: 23 January
Abstract: Complications are an undesired side effect of any treatment and radiotherapy is no different. The aim of this study was to quantify the burden of these side effects in a tertiary referral urology department. A prospective study of all urology admissions in a six-month period to a public urology department at a tertiary hospital was performed. Patients admitted with complications due to radiotherapy were included in the study. Data obtained included patient demographics, radiotherapy details, complication type and the management required. A total of 1198 patients were admitted; 921 (77%) were elective and 277 (23%) were emergency admissions. 13 out of 921 (1.4%) of elective admissions and 20 out of 277 (7.2%) of emergency admissions were due to radiotherapy complications. Radiotherapy complications was the fourth most common reason for emergency admission, ahead of acute urinary retention. 21 patients accounted for these 33 admissions. 39 separate complications due to radiotherapy were diagnosed, with some patients having multiple complications. The median time to onset of complication was four years, IQR (1-9). The surgical intervention rate was 67%. The commonest procedures were washout with/without clot evacuation or diathermy in theatre (15.8%) and urethral dilatation/bladder neck incision (15.8%). Two urinary diversions and two cystoprostatectomy & urinary diversion was performed. Radiotherapy complications are consequential and account for a significant proportion of a tertiary urology department's emergency workload. These complications generally occur years after radiotherapy and frequently require surgical intervention. This article is protected by copyright. All rights reserved.
DOI: 10.1111/bju.14145
ORCID: 0000-0002-5145-6783
PubMed URL: 29360286
PubMed URL:
Type: Journal Article
Appears in Collections:Journal articles

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