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Title: Relationship between Urinary Sodium-to-Potassium Ratio and Ambulatory Blood Pressure in Patients with Diabetes Mellitus
Authors: Libianto, Renata;Moran, John;O'Callaghan, Christopher J;Baqar, Sara;Chen, Angela X;Baker, Scott T;Clarke, Michelle V;Macisaac, Richard J;Jerums, George;Ekinci, Elif I
Issue Date: Jan-2018
EDate: 2017-09-16
Citation: Clinical and Experimental Pharmacology and Physiology 2018; 45(1): 94-97
Abstract: Previous studies investigating the relationship between sodium intake and blood pressure have mostly relied on dietary recall and clinic blood pressure measurement. In this cross-sectional study, we aimed to investigate the relationship between 24h urinary sodium and potassium excretion, and their ratio, with 24h ambulatory blood pressure parameters including nocturnal blood pressure dipping in patients with type 1 and 2 diabetes. We report that in 116 patients with diabetes, systolic blood pressure was significantly predicted by the time of day, age, the interaction between dipping status with time, and 24h urinary sodium-to-potassium ratio (R2 =0.83) with a relative contribution of 53%, 21%, 20% and 6%, respectively. However, there was no interaction between urinary sodium-to-potassium ratio and dipping status.
DOI: 10.1111/1440-1681.12852
ORCID: 0000-0003-2372-395X
PubMed URL:
Type: Journal Article
Subjects: ambulatory blood pressure
urinary electrolytes
Appears in Collections:Journal articles

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