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|Title:||Atypical small acinar proliferation and high grade prostatic intraepithelial neoplasia in the era of multi-parametric MRI: a contemporary review|
|Authors:||Manning, Todd G;Cheung, Ernest;Perera, Marlon;Christidis, Daniel;O'Brien, Jonathan S;Mitchell, Catherine;Bolton, Damien M;Lawrentschuk, Nathan L|
|Citation:||Urology 2017; online first: 21 April|
|Abstract:||Multiparametric Magnetic Resonance Imaging (mpMRI) has added to the armamentarium for the diagnosis and surveillance for organ confined prostate cancer. Atypical small acinar proliferation (ASAP) and high-grade prostatic intraepithelial neoplasia (HGPIN) are premalignant prostatic lesions. The management of such lesions remains contentious, and the addition of mpMRI introduces further uncertainty given its ability to pick up indolent lesions and its use in targeted biopsy. We aimed to perform a comprehensive review of current evidence regarding ASAP, HGPIN and mpMRI to ascertain a consensus for a current management algorithm.|
Atypical small acinar proliferation
High-grade prostatic intraepithelial neoplasia
Multiparametric Magnetic Resonance Imaging
|Appears in Collections:||Journal articles|
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