Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/16577
Title: Dietary supplement use in older people attending memory clinics in Australia
Authors: Cross, AJ;George, J;Woodward, Michael C;Ames, D;Brodaty, H;Elliott, Rohan A
Issue Date: Jan-2017
Citation: Journal of Nutrition, Health & Aging 2017; 21(1): 46-50
Abstract: BACKGROUND: Dietary supplement use is common in older adults. There has been limited research in people attending memory clinics. OBJECTIVES: To explore the use of dietary supplements in older people attending Australian memory clinics. DESIGN: Cross-sectional analysis of baseline data from the Prospective Research In MEmory clinics (PRIME) study. PARTICIPANTS: Community-dwelling older people who attended nine memory clinics and had a diagnosis of mild cognitive impairment (MCI) or dementia. MEASUREMENTS: Dietary supplement was defined as a product that contains one or more: vitamin, mineral, herb or other botanical, amino acid or other dietary substance. Non-prescribed supplement was defined as a supplement that is not usually prescribed by a medical practitioner. Polypharmacy was defined as use of five or more medications. RESULTS: 964 patients, mean age 77.6 years, were included. Dietary supplements were used by 550 (57.1%) patients; 353 (36.6%) used two or more. Non-prescribed supplements were used by 364 (36.8%) patients. Supplement use was associated with older age (OR: 1.12, 95% CI: 1.03-1.21), lower education level (OR: 1.53, 95% CI: 1.01-2.32) and a diagnosis of MCI rather than dementia (OR: 1.52, 95% CI: 1.05-2.21). Potential drug-supplement interactions were identified in 107 (11.1%) patients. Supplement users had increased prevalence of polypharmacy compared to non-users (80.5% vs. 48.1%, p<0.001). CONCLUSIONS: Dietary supplements, including non-prescribed supplements, were commonly used by people attending memory clinics. Supplement use increased the prevalence of polypharmacy and resulted in potential supplement-drug interactions. Further research is required to assess the clinical outcomes of supplement use.
URI: http://ahro.austin.org.au/austinjspui/handle/1/16577
DOI: 10.1007/s12603-016-0742-x
PubMed URL: https://www.ncbi.nlm.nih.gov/pubmed/27999849
Type: Journal Article
Appears in Collections:Journal articles

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