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Title: Drug-specific upregulation of CD137 on CD8+ T cells aids in the diagnosis of multiple antibiotic toxic epidermal necrolysis
Authors: Trubiano, Jason A;Redwood, Alec;Strautins, Kaija;Pavlos, Rebecca;Woolnough, Emily;Chang, Christina C;Phillips, Elizabeth
Issue Date: 22-Nov-2016
EDate: 2016-11-22
Citation: The Journal of Allergy and Clinical Immunology: In Practice 2016; online first: 22 November
Abstract: There are major challenges defining drug causality in cases of severe cutaneous adverse reactions (SCAR) involving multiple antibiotics. We describe a case of toxic epidermal necrolysis (TEN) occurring in the setting of multiple antibiotics and the use of IFN-γ enzyme-linked immunospot assay and flow cytometry to clarify causality.
DOI: 10.1016/j.jaip.2016.09.043
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Type: Journal Article
Type of Clinical Study or Trial: Case Series and Case Reports
Appears in Collections:Journal articles

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