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|Title:||Drug-specific upregulation of CD137 on CD8+ T cells aids in the diagnosis of multiple antibiotic toxic epidermal necrolysis|
|Authors:||Trubiano, Jason A;Redwood, Alec;Strautins, Kaija;Pavlos, Rebecca;Woolnough, Emily;Chang, Christina C;Phillips, Elizabeth|
|Citation:||The Journal of Allergy and Clinical Immunology: In Practice 2016; online first: 22 November|
|Abstract:||There are major challenges defining drug causality in cases of severe cutaneous adverse reactions (SCAR) involving multiple antibiotics. We describe a case of toxic epidermal necrolysis (TEN) occurring in the setting of multiple antibiotics and the use of IFN-γ enzyme-linked immunospot assay and flow cytometry to clarify causality.|
|Type of Clinical Study or Trial:||Case Series and Case Reports|
|Appears in Collections:||Journal articles|
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