Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16472
Full metadata record
DC FieldValueLanguage
dc.contributor.authorMurphy, C-
dc.contributor.authorHawkes, E-
dc.contributor.authorChionh, Fiona-
dc.contributor.authorChong, Geoff-
dc.date2016-10-28-
dc.date.accessioned2017-01-02T23:13:36Z-
dc.date.available2017-01-02T23:13:36Z-
dc.date.issued2017-02-
dc.identifier.citationJournal of Clinical Pharmacy and Therapeutics 2017; 42(1): 111-114en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/16472-
dc.description.abstractWHAT IS KNOWN AND OBJECTIVE: Human herpesvirus-8 (HHV-8)-positive, HIV-negative multicentric Castleman's disease is a rare lymphoproliferative disorder with no standardized treatment. Concurrent Kaposi's sarcoma, another HHV-8-related disease, is uncommon in HIV-negative patients. The role of antiviral therapy and rituximab in HIV-negative patients is not well established. CASE DESCRIPTION: We report a case of a 5-year, durable remission of HHV-8-positive, HIV-negative comorbid multicentric Castleman's disease and Kaposi's sarcoma treated with long-term valganciclovir, following initial rituximab and liposomal doxorubicin. WHAT IS NEW AND CONCLUSION: Currently, there is no defined role for antiviral therapy in the treatment of HIV-negative HHV-8-positive multicentric Castleman's disease and Kaposi's sarcoma. Ganciclovir followed by indefinite, continuous valganciclovir is thought to have contributed significantly to the durable response in this case.en_US
dc.subjectKaposi's sarcomaen_US
dc.subjectHuman herpesvirus-8en_US
dc.subjectMulticentric Castleman's diseaseen_US
dc.subjectValgancicloviren_US
dc.titleDurable remission of both multicentric Castleman's disease and Kaposi's sarcoma with valganciclovir, rituximab and liposomal doxorubicin in an HHV-8-positive, HIV-negative patienten_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Clinical Pharmacy and Therapeuticsen_US
dc.identifier.affiliationDepartment of Medical Oncology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationOlivia Newton-John Cancer Research Institute and School of Cancer Medicine, La Trobe University, Heidelberg, Victoria, Australiaen_US
dc.type.studyortrialCase Series and Case Reportsen_US
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/27790727en_US
dc.identifier.doi10.1111/jcpt.12472en_US
dc.type.contentTexten_US
dc.type.austinJournal Articleen_US
local.name.researcherHawkes, Eliza A
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeJournal Article-
crisitem.author.deptClinical Haematology-
crisitem.author.deptOlivia Newton-John Cancer Wellness and Research Centre-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

14
checked on Mar 28, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.