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Title: MRI correlates of general intelligence in neurotypical adults
Authors: Malpas, Charles B;Genc, Sila;Saling, Michael M;Velakoulis, Dennis;Desmond, Patricia M;O’Brien, Terence J
Issue Date: Feb-2016
EDate: 2015-10-09
Citation: Journal of Clinical Neuroscience 2016; 24: 128-134
Abstract: There is growing interest in the neurobiological substrate of general intelligence. Psychometric estimates of general intelligence are reduced in a range of neurological disorders, leading to practical application as sensitive, but non-specific, markers of cerebral disorder. This study examined estimates of general intelligence in neurotypical adults using diffusion tensor imaging and resting-state functional connectivity analysis. General intelligence was related to white matter organisation across multiple brain regions, confirming previous work in older healthy adults. We also found that variation in general intelligence was related to a large functional sub-network involving all cortical lobes of the brain. These findings confirm that individual variance in general intelligence is related to diffusely represented brain networks.
DOI: 10.1016/j.jocn.2015.07.012
PubMed URL:
Type: Journal Article
Subjects: Diffusion MRI
Functional connectivity
Resting state
White matter
Appears in Collections:Journal articles

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