Please use this identifier to cite or link to this item:
|Title:||Sepsis-Induced acute kidney injury|
|Authors:||Mårtensson, Johan;Bellomo, Rinaldo|
|Citation:||Critical Care Clinics 2015; 31(4): 649-660|
|Abstract:||Acute kidney injury (AKI) is a serious yet potentially reversible complication of sepsis. Several molecular mechanisms involved in the development of septic AKI have been identified. These mechanisms may be important targets in the development of future therapies. This review highlights the role of the innate immune response to sepsis and its downstream effects on kidney structure and function with special reference to the adaptive cellular response and glomerular hemodynamic changes. In addition, current evidence surrounding the management of patients with septic AKI is summarized. Finally, potential novel therapies for septic AKI are presented.|
|Subjects:||Acute kidney injury|
Renal replacement therapy
|Appears in Collections:||Journal articles|
Files in This Item:
There are no files associated with this item.
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.