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Title: Field walking tests are reliable and responsive to exercise training in people with non-cystic fibrosis bronchiectasis
Authors: Lee, Annemarie L;Cecins, Nola;Holland, Anne E;Hill, Catherine J;McDonald, Christine F;Burge, Angela T;Rautela, Linda;Thompson, Philip J;Stirling, Robert G;Jenkins, Sue
Issue Date: Nov-2015
Citation: Journal of Cardiopulmonary Rehabilitation & Prevention 2015; 35(6): 439-445
Abstract: PURPOSE: The 6-Minute Walk Test (6MWT) and Incremental Shuttle Walk Test (ISWT) are used to assess exercise capacity, but the reliability and responsiveness of these tests in individuals with non-cystic fibrosis (CF) bronchiectasis have not been determined. This study aimed to determine the reliability and responsiveness of both tests in adults with non-CF bronchiectasis. METHODS: Eighty-five participants completed 2 6MWTs and 2 ISWTs in random order. Testing was repeated at the conclusion of an 8-week intervention period of exercise training. Reliability was assessed using intraclass correlation coefficients (ICC) and Bland-Altman analysis. Responsiveness was measured by effect size (ES) and standardized response mean (SRM). RESULTS: At baseline, test-retest reliability was high for both tests (ICC ≥ 0.95). The mean (95% CI) increase in the 6MWT from test 1 to test 2 was 20 m (13-26 m): 3% (0-5%) change. The mean (95% CI) increase in the ISWT was 15 m (4-25m): 4% (2-6%) change. A significant learning effect persisted after 8 weeks for the 6MWT (P = .04), but not the ISWT (P = .61). The 6MWT ES was 0.32 and SRM was 0.68; for the ISWT, ES was 0.42 with SRM of 0.71. CONCLUSION: The 6MWT and ISWT are reliable measures of exercise capacity in non-CF bronchiectasis and responsive to exercise training. The small learning effect in both measures at baseline suggests that 2 of each test are necessary to correctly assess exercise capacity. Completion of 2 6MWTs at followup may minimize the risk of underestimating a treatment effect. TRIAL REGISTRATION: NCT00885521.
DOI: 10.1097/HCR.0000000000000130
PubMed URL:
Type: Journal Article
Subjects: Bronchiectasis
Exercise Test
Oxygen Consumption
Exercise Tolerance
Appears in Collections:Journal articles

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