Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16127
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dc.contributor.authorVillemagne, Victor L-
dc.contributor.authorRowe, Christopher C-
dc.contributor.authorOkamura, Nobuyuki-
dc.date.accessioned2016-08-15T06:08:07Z-
dc.date.available2016-08-15T06:08:07Z-
dc.date.issued2016-06-04-
dc.identifier.citationAlzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring 2016; 4: 39-42en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/16127-
dc.description.abstractIn vivo imaging of tau deposits is providing a better understanding of the temporal and spatial tau deposition in the brain, allowing a more comprehensive insight into the causes, diagnoses, and potentially treatment of tauopathies such as Alzheimer's disease, progressive supranuclear palsy, corticobasal syndrome, chronic traumatic encephalopathy, and some variants of frontotemporal lobar degeneration. The assessment of tau deposition in the brain over time will allow a deeper understanding of the relationship between tau and other variables such as cognition, genotype, and neurodegeneration, as well as assessing the role tau plays in ageing. Preliminary human studies suggest that tau imaging could also be used as a diagnostic, prognostic, and theranostic biomarker, as well as a surrogate marker for target engagement, patient recruitment, and efficacy monitoring for disease-specific therapeutic trials.en
dc.subjectPETen
dc.subjectTau imagingen
dc.subjectAlzheimer's diseaseen
dc.subjectPositron emission tomographyen
dc.subjectTauopathiesen
dc.subjectDementiaen
dc.titleUntangling tau imagingen
dc.typeJournal Articleen
dc.identifier.journaltitleAlzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoringen
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationMolecular Imaging and Therapyen
dc.identifier.affiliationThe Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Medicine, The University of Melbourne, Parkville, Australiaen
dc.identifier.affiliationDepartment of Pharmacology, Tohoku University, Sendai, Japanen
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/27489878en
dc.identifier.doi10.1016/j.dadm.2016.05.001en
dc.type.contentTexten
dc.identifier.orcid0000-0003-3910-2453en
dc.type.austinJournal Articleen_US
local.name.researcherRowe, Christopher C
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeJournal Article-
crisitem.author.deptMolecular Imaging and Therapy-
crisitem.author.deptMolecular Imaging and Therapy-
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