Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16103
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dc.contributor.authorLister, David M-
dc.contributor.authorKotsanas, Despina-
dc.contributor.authorBallard, Susan A-
dc.contributor.authorHowden, Benjamin P-
dc.contributor.authorCarse, Elizabeth-
dc.contributor.authorTan, Kenneth-
dc.contributor.authorScott, Carmel-
dc.contributor.authorGillespie, Elizabeth E-
dc.contributor.authorMahony, Andrew A-
dc.contributor.authorDoherty, Richard-
dc.contributor.authorKorman, Tony M-
dc.contributor.authorJohnson, Paul D R-
dc.contributor.authorStuart, Rhonda L-
dc.date2015-07-17-
dc.date.accessioned2016-08-03T06:01:54Z-
dc.date.available2016-08-03T06:01:54Z-
dc.date.issued2015-10-01-
dc.identifier.citationAmerican Journal of Infection Control 2015; 43(10): 1061-1065en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/16103-
dc.description.abstractOBJECTIVE: To describe successful termination of an outbreak of vancomycin-resistant Enterococcus faecium (VREfm) colonization within a neonatal service. SETTING: Multisite neonatal intensive care unit and special care nurseries within a single health care service. PARTICIPANTS: Forty-four cases of VREfm-colonized neonatal inpatients-including 2 clinical isolates (eye swab and catheter-urine specimen) and 42 screening isolates. INTERVENTIONS: Active surveillance cultures, patient isolation, contact precautions, enhanced environment cleaning, and staff and parent education. Whole genome sequencing and multilocus sequence typing were used to characterize the outbreak and refine infection control procedures. RESULTS: Peak prevalence of VREfm colonization across all sites was 31% upon discovery of the outbreak. Subsequent to the intervention, transmission was halted within 8 weeks and no further isolates of the outbreak strain have been detected as of 12 months following outbreak cessation. Environmental swabs revealed VREfm colonization of baby-weighing scales, a baby bath, and a pharmacy refrigerator within the neonatal intensive care unit. All isolates were of a single multilocus sequence type (sequence type 796) and highly clonal at the core genome level. CONCLUSIONS: Bundled infection control interventions were effective in rapidly terminating a clonal outbreak of sequence type 796 VREfm colonization within a neonatal inpatient service. Strain-typing and active surveillance cultures were critical in guiding the management of this outbreak. The closed environment of a neonatal unit likely facilitated eradication of the patient and environment reservoirs of VREfm colonization.en_US
dc.subjectEnvironment cleaningen_US
dc.subjectInfection controlen_US
dc.subjectNeonatesen_US
dc.subjectWhole genome sequencingen_US
dc.titleOutbreak of vanB vancomycin-resistant Enterococcus faecium colonization in a neonatal serviceen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleAmerican Journal of Infection Controlen_US
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationMonash Infectious Diseases, Monash Health, Clayton, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Microbiology, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationMicrobiological Diagnostic Unit Public Health Laboratory, The University of Melbourne, Parkville, Victoria, Australiaen_US
dc.identifier.affiliationMonash Childrens Hospital, Monash Health, Clayton, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Infection Prevention & Epidemiology, Monash Health, Clayton, Victoria, Australiaen_US
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/26190380en_US
dc.identifier.doi10.1016/j.ajic.2015.05.047en_US
dc.type.contentTexten_US
dc.type.austinJournal Articleen_US
local.name.researcherHowden, Benjamin P
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.openairetypeJournal Article-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptMicrobiology-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptInfectious Diseases-
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