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|Title:||Differential characteristics and localisation of [3H]oxazoline and [3H]imidazoline binding sites in rat kidney.|
|Authors:||King, P R;Suzuki, Satoshi;Louis, William J;Gundlach, Andrew L|
|Affiliation:||University of Melbourne, Department of Medicine, Austin and Repatriation Medical Centre, Heidelberg, Vic., Australia.|
|Citation:||European Journal of Pharmacology; 281(3): 341-6|
|Abstract:||Comparative autoradiography revealed that the imidazolines [3H]p-aminoclonidine and [3H]idazoxan labelled high densities of alpha 2A-adrenoceptor sites in the inner medulla and inner stripe of the outer medulla of rat kidney. In contrast, the oxazoline [3H]rilmenidine labelled a high density of non-adrenergic sites in the cortex and outer stripe of the outer medulla, a lower density in the inner stripe and inner medulla and a low density of alpha 2A-adrenoceptor sites in inner medulla. The existence of novel, non-adrenergic oxazoline sites of potential functional importance in rat kidney has important implications for the classification of imidazoline receptors.|
|Internal ID Number:||8521919|
Rats, Inbred WKY
|Appears in Collections:||Journal articles|
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