Please use this identifier to cite or link to this item:
|Title:||Prolactin response to dl-fenfluramine in panic disorder.|
|Authors:||Apostolopoulos, M;Judd, F K;Burrows, Graham D;Norman, Trevor R|
|Affiliation:||University of Melbourne, Department of Psychiatry, Austin Hospital, Heidelberg, Victoria, Australia.|
|Citation:||Psychoneuroendocrinology; 18(5-6): 337-42|
|Abstract:||The objective of this study was to test the hypothesis that serotonin receptors are hypersensitive in patients with panic disorder. Eleven patients and 12 controls received a single PO dose of 60 mg of dl-fenfluramine at 0900h on a single occasion. Blood samples were collected with an indwelling intravenous catheter at 30-min intervals from 0930h to 1530h and prolactin determined by radioimmunoassay. In both groups, fenfluramine induced a rise in the plasma prolactin concentration from baseline. The patients showed a greater increase in prolactin response than the normal controls. This result is consistent with the hypothesis of increased serotonin receptor function in patients with panic disorder.|
|Internal ID Number:||8416044|
Receptors, Serotonin.drug effects.physiology
|Appears in Collections:||Journal articles|
Files in This Item:
There are no files associated with this item.
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.