Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/13352
Title: Corpus callosotomy for intractable epilepsy: seizure outcome and prognostic factors.
Authors: Reutens, David C;Bye, A M;Hopkins, I J;Danks, A;Somerville, E;Walsh, J;Bleasel, A;Ouvrier, R;MacKenzie, R A;Manson, J I
Affiliation: Department of Neurology, Austin Hospital, Heidelberg, Victoria, Australia.
Issue Date: 10-Sep-1993
Citation: Epilepsia; 34(5): 904-9
Abstract: We reviewed the outcome of corpus callosal section in 64 adult and pediatric patients to identify factors associated with a good outcome: 48% of patients had a favorable outcome for overall seizure frequency. Improvement was noted in several seizure types and was most likely for drop attacks, particularly in the setting of a unilateral focal cerebral lesion or a true generalized epilepsy of Lennox-Gastaut type. Poor outcomes for drop attacks were more likely if there was associated severe intellectual handicap or bilateral independent spikes on interictal EEG. Complex partial seizures (CPS), most commonly of frontal lobe origin, also responded favorably. The complications of callosal section were usually mild and transient. New focal seizures occurred in only 2 patients and were not as frequent or disabling as preoperative seizures types. A worthwhile improvement in seizure outcome was achieved by completion of the callosotomy in 6 of 10 patients with unsatisfactory results from anterior callosotomy.
Internal ID Number: 8404745
URI: http://ahro.austin.org.au/austinjspui/handle/1/13352
URL: http://www.ncbi.nlm.nih.gov/pubmed/8404745
Type: Journal Article
Subjects: Adolescent
Adult
Aged
Child
Child, Preschool
Corpus Callosum.surgery
Electroencephalography
Epilepsy.diagnosis.physiopathology.surgery
Epilepsy, Complex Partial.diagnosis.physiopathology.surgery
Epilepsy, Generalized.diagnosis.physiopathology.surgery
Female
Follow-Up Studies
Functional Laterality
Humans
Male
Middle Aged
Prognosis
Recurrence
Retrospective Studies
Treatment Outcome
Appears in Collections:Journal articles

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