Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/13273
Title: Serotonergic function in panic disorder: endocrine responses to D-fenfluramine.
Authors: Judd, F K;Apostolopoulos, M;Burrows, Graham D;Norman, Trevor R
Affiliation: Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia.
Issue Date: 1-Mar-1994
Citation: Progress in Neuro-psychopharmacology & Biological Psychiatry; 18(2): 329-37
Abstract: 1. Prolactin and cortisol responses to d-fenfluramine were measured in 16 patients with DSM-III-R panic disorder and 14 normal controls. 2. Patients showed a greater mean prolactin response than controls but the difference between groups was not statistically significant (P > 0.05, MANOVA). 3. No consistent differences were observed between patients and controls with respect to cortisol responses (P > 0.05, MANOVA). 4. The results do not support the hypothesis of hypersensitive post-synaptic serotonin receptors in patients with panic disorder. 5. Studies in larger groups are necessary to confirm the trend and to explore receptor subtype sensitivity.
Internal ID Number: 8208982
URI: http://ahro.austin.org.au/austinjspui/handle/1/13273
URL: http://www.ncbi.nlm.nih.gov/pubmed/8208982
Type: Journal Article
Subjects: Adult
Female
Fenfluramine.therapeutic use
Hormones.blood
Humans
Hydrocortisone.blood
Male
Panic Disorder.blood.drug therapy.physiopathology
Prolactin.blood
Psychiatric Status Rating Scales
Receptors, Serotonin.drug effects
Serotonin.physiology
Appears in Collections:Journal articles

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