Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/13223
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSeeman, Egoen
dc.contributor.authorTsalamandris, Conen
dc.contributor.authorFormica, Cen
dc.contributor.authorHopper, John Len
dc.contributor.authorMcKay, Jen
dc.date.accessioned2015-05-16T03:02:14Z
dc.date.available2015-05-16T03:02:14Z
dc.date.issued1994-05-01en
dc.identifier.citationJournal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research; 9(5): 739-43en
dc.identifier.govdoc8053404en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/13223en
dc.description.abstractLow bone density in women with hip fractures ("senile" osteoporosis) may be due to excessive bone loss or low peak bone density. If excessive bone loss is responsible, then no reduction in bone density is expected in their daughters. If low peak bone density is responsible, then bone density should also be reduced in their daughters because genetic and family environmental factors influence the variability in bone density. Bone density was measured using dual-photon absorptiometry and expressed as a standardized deviation or Z score relative to 697 controls, adjusting for age, height, weight, and menopausal status. In 74 women with hip fractures, the Z score (mean +/- SEM) was -0.52 +/- 0.14 (P < 0.001) at the femoral neck, -1.04 +/- 0.17 (P < 0.001) at the femoral shaft, and -0.43 +/- 0.10 (P < 0.001) at the lumbar spine. In their 41 daughters, the Z score was -0.40 +/- 0.17 (P < 0.05) at the femoral neck, -0.41 +/- 0.19 (P < 0.001) at the femoral shaft, and 0.23 +/- 0.13 (NS) at the lumbar spine. We conclude that daughters of women with hip fractures are likely to be at increased risk for hip fractures themselves because they have reduced femoral neck bone density. Femoral neck fractures may not be entirely attributable to trauma; reduced bone density is likely to contribute and may be caused by the attainment of a lower peak femoral neck bone density.en
dc.language.isoenen
dc.subject.otherAbsorptiometry, Photonen
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherBone Density.physiologyen
dc.subject.otherFemaleen
dc.subject.otherFemur Neck.physiologyen
dc.subject.otherHip Fractures.etiologyen
dc.subject.otherHumansen
dc.subject.otherMiddle Ageden
dc.subject.otherOsteoporosis.etiologyen
dc.subject.otherOsteoporosis, Postmenopausal.etiologyen
dc.titleReduced femoral neck bone density in the daughters of women with hip fractures: the role of low peak bone density in the pathogenesis of osteoporosis.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Bone and Mineral Researchen
dc.identifier.affiliationDepartment of Medicine, Austin Hospital Faculty of Medicine, Melbourne, Victoria, Australiaen
dc.identifier.doi10.1002/jbmr.5650090520en
dc.description.pages739-43en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/8053404en
dc.type.austinJournal Articleen
local.name.researcherSeeman, Ego
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.deptEndocrinology-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

6
checked on Mar 27, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.