Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/13186
Title: Day-night blood pressure variation in normotensive, normoalbuminuric type I diabetic subjects. Dippers and non-dippers.
Authors: Gilbert, Richard E;Phillips, P A;Clarke, C;Jerums, George
Affiliation: Endocrinology Unit, Austin Hospital, Heidelberg, Victoria, Australia.
Issue Date: 1-Aug-1994
Citation: Diabetes Care; 17(8): 824-7
Abstract: To examine day-night blood pressure (BP) variation in normotensive, normoalbuminuric subjects with type I diabetes and to assess the prevalence of an impaired nocturnal BP fall.Fourteen healthy volunteers and 13 normotensive, normoalbuminuric subjects with type I diabetes were studied with an ambulatory sphygmomanometric device for 24 h.No significant difference was found between diabetic and control groups with regard to daytime systolic blood pressure (sBP) or diastolic blood pressure (dBP). However, the mean nighttime sBPs (P < 0.01) and dBPs (P = 0.01) were significantly higher in the diabetic group compared with the control group. Furthermore, the night/day ratio for both sBP (P < 0.01) and dBP (P < 0.01) was significantly higher in the diabetic group. Approximately half of the diabetic subjects studied were non-dippers when defined either by a nocturnal fall in sBP/dBP of < 10/5 mmHg (5/13 vs. 0/14, P < 0.05: diabetic group vs. control group) or a day to night fall in either sBP (7/13 vs. 2/14, P < 0.05) or dBP (6/13 vs. 0/14, P < 0.01) of < 10%.Ambulatory BP may reveal impaired nocturnal BP fall in normotensive, normoalbuminuric subjects with type I diabetes. These subjects may be at greater risk of certain complications as a consequence of an increased BP burden.
Internal ID Number: 7956625
URI: http://ahro.austin.org.au/austinjspui/handle/1/13186
URL: http://www.ncbi.nlm.nih.gov/pubmed/7956625
Type: Journal Article
Subjects: Adult
Albuminuria
Blood Pressure
Blood Pressure Monitoring, Ambulatory
Circadian Rhythm
Diabetes Mellitus, Type 1.physiopathology
Diastole
Female
Humans
Male
Reference Values
Systole
Appears in Collections:Journal articles

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