Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/13175
Title: Definition and differential diagnosis of treatment-resistant depression.
Authors: Burrows, Graham D;Norman, Trevor R;Judd, F K
Affiliation: Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia.
Issue Date: 1-Jun-1994
Citation: International Clinical Psychopharmacology; 9 Suppl 2(): 5-10
Abstract: There are no agreed criteria for treatment-resistant depression, but the failure to respond adequately to two successive courses of monotherapy with pharmacologically different antidepressants, given in an adequate dose for sufficient time is one pragmatic definition. Inherent within this definition are notions of what constitutes an adequate dose of drug, the length of treatment and pharmacological specificity of treatments. When these factors are accounted for, treatment resistance may be encountered in 15-20% of patients. In attempting to treat such patients a number of pharmacological strategies have been adopted and some are briefly reviewed. Psychosurgery may have a role to play in cases of absolute treatment resistance.
Internal ID Number: 7930496
URI: http://ahro.austin.org.au/austinjspui/handle/1/13175
URL: http://www.ncbi.nlm.nih.gov/pubmed/7930496
Type: Journal Article
Subjects: Antidepressive Agents.administration & dosage.therapeutic use
Depressive Disorder.diagnosis.drug therapy.psychology.therapy
Diagnosis, Differential
Drug Resistance
Humans
Terminology as Topic
Appears in Collections:Journal articles

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