Please use this identifier to cite or link to this item:
|Title:||Interactions of angiotensin II with central catecholamines.|
|Authors:||Jenkins, T A;Allen, A M;Chai, Syn Y;Mendelsohn, Frederick AO|
|Affiliation:||Department of Medicine, University of Melbourne, Austin Hospital Heidelberg, Victoria.|
|Citation:||Clinical and Experimental Hypertension (new York, N.y. : 1993); 17(1-2): 267-80|
|Abstract:||There is a large body of anatomical and functional evidence supporting an interaction between brain angiotensin and central catecholamine systems. Angiotensin II AT1 receptors have been identified on dopamine containing cells in the substantia nigra and striatum of human brain using receptor autoradiography. Using in vivo microdialysis we have demonstrated that locally administered angiotensin II stimulates dopamine release from the striatum of conscious rats. Since some angiotensin receptor antagonists and angiotensin converting enzyme inhibitors can cross the blood brain barrier it is possible that they interact with the brain catecholaminergic systems.|
|Internal ID Number:||7735274|
Angiotensin Receptor Antagonists
Angiotensin-Converting Enzyme Inhibitors.pharmacology
|Appears in Collections:||Journal articles|
Files in This Item:
There are no files associated with this item.
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.