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Title: | Regional brain concentrations of cholecystokinin in the rat: the effects of kindled and non-kindled seizures. | Austin Authors: | Harris, Q L;Lewis, S J;Shulkes, Arthur;Vajda, F J;Jarrott, B | Affiliation: | University of Melbourne, Austin Hospital, Victoria, Australia | Issue Date: | 1-May-1988 | Publication information: | Neuropharmacology; 27(5): 547-50 | Abstract: | In an attempt to understand the neurochemical basis of kindling, this study investigated the effects on brain cholecystokinin (CCK) of amygdaloid kindled and non-kindled seizures. Thirteen brain regions were examined in rats sacrificed either 24 hr or 3 weeks after the last kindled seizure, or 24 hr after a suprathreshold stimulation-induced (non-kindled) seizure; and in sham kindled rats. There were no significant differences in CCK immunoreactivity between any of these groups. These results do not confirm a previous report of an increase in CCK in the hippocampus following amygdaloid kindling in the rat. | Gov't Doc #: | 3393271 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/12979 | Journal: | Neuropharmacology | URL: | https://pubmed.ncbi.nlm.nih.gov/3393271 | Type: | Journal Article | Subjects: | Animals Brain.anatomy & histology Brain Chemistry.drug effects Cholecystokinin.metabolism Kindling, Neurologic Male Organ Size Radioimmunoassay Rats Rats, Inbred Strains Seizures.metabolism |
Appears in Collections: | Journal articles |
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