Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12925
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dc.contributor.authorJarrott, Ben
dc.contributor.authorLewis, S Jen
dc.contributor.authorMaccarrone, Cen
dc.contributor.authorShulkes, Arthuren
dc.date.accessioned2015-05-16T02:41:15Z
dc.date.available2015-05-16T02:41:15Z
dc.date.issued1988-02-01en
dc.identifier.citationClinical and Experimental Pharmacology & Physiology; 15(2): 157-62en
dc.identifier.govdoc3078273en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12925en
dc.description.abstract1. Spontaneously hypertensive rats (SHR) are useful for investigating the possible pathophysiological and neurochemical basis of human essential hypertension. 2. The accepted pathogenic mechanism of hypertension in SHR is an increased central sympathetic drive which results in an increased peripheral resistance. 3. The neurochemical basis of the increased sympathetic drive is unknown. The observation that there are reduced levels of neuropeptides (vasoactive intestinal peptide, neuropeptide Y, cholecystokinin octapeptide, neurotensin and calcitonin gene related peptide) in the spinal cord in SHR rats compared with age and gender matched Wistar-Kyoto normotensive rats could provide a basis for understanding the mechanism of hypertension in SHR.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherHypertension.metabolismen
dc.subject.otherMedulla Oblongata.metabolismen
dc.subject.otherNeuropeptides.metabolismen
dc.subject.otherRatsen
dc.subject.otherRats, Inbred SHRen
dc.subject.otherSpinal Cord.metabolismen
dc.titleAltered levels of neuropeptides in the medulla and spinal cord of spontaneously hypertensive rats.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical and Experimental Pharmacology & Physiologyen
dc.identifier.affiliationDepartment of Medicine, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages157-62en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/3078273en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
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