Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12507
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dc.contributor.authorKlunk, William Een
dc.contributor.authorKoeppe, Robert Aen
dc.contributor.authorPrice, Julie Cen
dc.contributor.authorBenzinger, Tammie Len
dc.contributor.authorDevous, Michael Den
dc.contributor.authorJagust, William Jen
dc.contributor.authorJohnson, Keith Aen
dc.contributor.authorMathis, Chester Aen
dc.contributor.authorMinhas, Davneeten
dc.contributor.authorPontecorvo, Michael Jen
dc.contributor.authorRowe, Christopher Cen
dc.contributor.authorSkovronsky, Daniel Men
dc.contributor.authorMintun, Mark Aen
dc.date.accessioned2015-05-16T02:12:50Z
dc.date.available2015-05-16T02:12:50Z
dc.date.issued2014-10-28en
dc.identifier.citationAlzheimer's & Dementia : the Journal of the Alzheimer's Association 2014; 11(1): 1-15.e1-4en
dc.identifier.govdoc25443857en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12507en
dc.description.abstractAlthough amyloid imaging with PiB-PET ([C-11]Pittsburgh Compound-B positron emission tomography), and now with F-18-labeled tracers, has produced remarkably consistent qualitative findings across a large number of centers, there has been considerable variability in the exact numbers reported as quantitative outcome measures of tracer retention. In some cases this is as trivial as the choice of units, in some cases it is scanner dependent, and of course, different tracers yield different numbers. Our working group was formed to standardize quantitative amyloid imaging measures by scaling the outcome of each particular analysis method or tracer to a 0 to 100 scale, anchored by young controls (≤ 45 years) and typical Alzheimer's disease patients. The units of this scale have been named "Centiloids." Basically, we describe a "standard" method of analyzing PiB PET data and then a method for scaling any "nonstandard" method of PiB PET analysis (or any other tracer) to the Centiloid scale.en
dc.language.isoenen
dc.subject.otherAmyloid imagingen
dc.subject.otherCentiloid scaleen
dc.subject.otherPittsburgh compound Ben
dc.subject.otherPositron emission tomographyen
dc.subject.otherStandardizeen
dc.titleThe Centiloid Project: standardizing quantitative amyloid plaque estimation by PET.en
dc.typeJournal Articleen
dc.identifier.journaltitleAlzheimer's & dementia : the journal of the Alzheimer's Associationen
dc.identifier.affiliationDepartment of Radiology, UT Southwestern Medical Center, Dallas, TX, USAen
dc.identifier.affiliationDepartment of Neurology, UT Southwestern Medical Center, Dallas, TX, USAen
dc.identifier.affiliationDepartment of Radiology, University of Michigan, Ann Arbor, MI, USAen
dc.identifier.affiliationDepartment of Neurology, University of Pittsburgh, Pittsburgh. PA, USAen
dc.identifier.affiliationDepartment of Radiology, Massachusetts General Hospital, Boston, MA, USAen
dc.identifier.affiliationDepartment of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, Victoria, Australia, Australiaen
dc.identifier.affiliationDepartment of Neurology, Massachusetts General Hospital, Boston, MA, USAen
dc.identifier.affiliationDepartments of Radiology, Pharmacology and Biological Chemistry, and Pharmaceutical Sciences, University of Pittsburgh, Pittsburgh, PA, USAen
dc.identifier.affiliationHelen Wills Neuroscience Institute, University of California Berkeley, Berkeley, CA, USAen
dc.identifier.affiliationDepartment of Neurosurgery, Washington University, Saint Louis, MO, USAen
dc.identifier.affiliationDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USAen
dc.identifier.affiliationAvid Radiopharmaceuticals, Philadelphia, PA, USAen
dc.identifier.affiliationDepartment of Radiology, University of Pittsburgh, Pittsburgh, PA, USAen
dc.identifier.doi10.1016/j.jalz.2014.07.003en
dc.description.pages1-15.e1-4en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/25443857en
dc.type.austinJournal Articleen
local.name.researcherRowe, Christopher C
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptMolecular Imaging and Therapy-
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