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Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Phillips, P A | en |
dc.contributor.author | Sasadeus, J | en |
dc.contributor.author | Hodsman, G P | en |
dc.contributor.author | Horowitz, J D | en |
dc.contributor.author | Saltups, A | en |
dc.contributor.author | Johnston, Colin I | en |
dc.date.accessioned | 2015-05-16T02:05:10Z | |
dc.date.available | 2015-05-16T02:05:10Z | |
dc.date.issued | 1989-02-01 | en |
dc.identifier.citation | British Heart Journal; 61(2): 139-43 | en |
dc.identifier.govdoc | 2522310 | en |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/12392 | en |
dc.description.abstract | Plasma concentrations of immunoreactive atrial natriuretic peptide (mean (SEM] were measured in 135 patients admitted to two coronary care units with myocardial infarction, ischaemic chest pain, or non-ischaemic chest pain. Concentrations were significantly higher in patients with acute myocardial infarction not treated with systemic thrombolysis (60.4 (14.3) pg/ml) than in patients with non-ischaemic chest pain (21.1 (4.3) pg/ml). Patients with ischaemic chest pain had intermediate values (39.3 (7.1) pg/ml). Patients with acute myocardial infarction treated with intravenous streptokinase had normal concentrations of plasma atrial natriuretic peptide (20.2 (3.6) pg/mg), which were significantly lower than those in patients with myocardial infarction not given streptokinase. These changes could not be explained by factors such as age, pre-existing hypertension, renal dysfunction, or cardiac failure, nor treatment other than streptokinase. Raised plasma concentrations of atrial natriuretic peptide in acute myocardial infarction may be a homoeostatic response acting to reduce atrial pressures by natriuresis, diuresis, and venodilatation. The lower concentrations of atrial natriuretic peptide in patients with acute myocardial infarction treated with streptokinase may reflect a short term beneficial haemodynamic effect of streptokinase. | en |
dc.language.iso | en | en |
dc.subject.other | Angina Pectoris.blood | en |
dc.subject.other | Atrial Natriuretic Factor.blood | en |
dc.subject.other | Chest Pain.blood | en |
dc.subject.other | Female | en |
dc.subject.other | Humans | en |
dc.subject.other | Male | en |
dc.subject.other | Middle Aged | en |
dc.subject.other | Myocardial Infarction.blood.drug therapy | en |
dc.subject.other | Streptokinase.therapeutic use | en |
dc.title | Plasma atrial natriuretic peptide in patients with acute myocardial infarction: effects of streptokinase. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | British heart journal | en |
dc.identifier.affiliation | Department of Medicine, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia | en |
dc.description.pages | 139-43 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/2522310 | en |
dc.type.austin | Journal Article | en |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.fulltext | No Fulltext | - |
item.grantfulltext | none | - |
item.languageiso639-1 | en | - |
item.openairetype | Journal Article | - |
Appears in Collections: | Journal articles |
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