Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/12357
Title: Lack of effect of the antidepressant compound bupropion on pineal indoleamines.
Authors: McIntyre, I M;Oxenkrug, G F
Affiliation: Department of Psychiatry, University of Melbourne & Austin Hospital, Heidelberg, Australia.
Issue Date: 1-Nov-1989
Citation: Pharmacopsychiatry; 22(6): 263-5
Abstract: The effects of the antidepressant compound bupropion were studied on rat pineal indoleamines. A pharmacologically relevant dose of bupropion either acutely (20 mg/kg) or chronically (20 mg/kg/day for 12 days) had no significant effect on pineal melatonin synthesis or other pineal indoleamine concentrations. The significance of this finding is discussed in relation to the lack of effect of bupropion on beta-adrenergic receptors.
Internal ID Number: 2515551
URI: http://ahro.austin.org.au/austinjspui/handle/1/12357
URL: http://www.ncbi.nlm.nih.gov/pubmed/2515551
Type: Journal Article
Subjects: Animals
Antidepressive Agents.pharmacology
Biogenic Monoamines.metabolism
Bupropion
Indoles.metabolism
Male
Melatonin.metabolism
Pineal Gland.drug effects.metabolism
Propiophenones.pharmacology
Rats
Rats, Inbred Strains
Appears in Collections:Journal articles

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