Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12228
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dc.contributor.authorHickson, Kevin Jen
dc.contributor.authorO'Keefe, Graeme Jen
dc.date.accessioned2015-05-16T01:53:08Z
dc.date.available2015-05-16T01:53:08Z
dc.date.issued2014-05-25en
dc.identifier.citationAustralasian Physical & Engineering Sciences in Medicine / Supported By the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicine 2014; 37(3): 495-503en
dc.identifier.govdoc24859803en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12228en
dc.description.abstractThe scalable XCAT voxelised phantom was used with the GATE Monte Carlo toolkit to investigate the effect of voxel size on dosimetry estimates of internally distributed radionuclide calculated using direct Monte Carlo simulation. A uniformly distributed Fluorine-18 source was simulated in the Kidneys of the XCAT phantom with the organ self dose (kidney ← kidney) and organ cross dose (liver ← kidney) being calculated for a number of organ and voxel sizes. Patient specific dose factors (DF) from a clinically acquired FDG PET/CT study have also been calculated for kidney self dose and liver ← kidney cross dose. Using the XCAT phantom it was found that significantly small voxel sizes are required to achieve accurate calculation of organ self dose. It has also been used to show that a voxel size of 2 mm or less is suitable for accurate calculations of organ cross dose. To compensate for insufficient voxel sampling a correction factor is proposed. This correction factor is applied to the patient specific dose factors calculated with the native voxel size of the PET/CT study.en
dc.language.isoenen
dc.subject.otherComputer Simulationen
dc.subject.otherDose-Response Relationship, Radiationen
dc.subject.otherFluorodeoxyglucose F18.diagnostic useen
dc.subject.otherHumansen
dc.subject.otherKidney.radiography.radionuclide imagingen
dc.subject.otherMonte Carlo Methoden
dc.subject.otherPhantoms, Imagingen
dc.subject.otherRadiographic Image Interpretation, Computer-Assisteden
dc.subject.otherRadiometry.methodsen
dc.titleEffect of voxel size when calculating patient specific radionuclide dosimetry estimates using direct Monte Carlo simulation.en
dc.typeJournal Articleen
dc.identifier.journaltitleAustralasian physical & engineering sciences in medicine / supported by the Australasian College of Physical Scientists in Medicine and the Australasian Association of Physical Sciences in Medicineen
dc.identifier.affiliationCentre for PET, Austin Health, Studley Rd, Heidelberg, VIC, 3084, Australia,en
dc.identifier.doi10.1007/s13246-014-0277-6en
dc.description.pages495-503en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24859803en
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextopen-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
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