Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/12107
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dc.contributor.authorCampbell, Robert Nen
dc.contributor.authorLiew, Mun Semen
dc.contributor.authorGan, Hui Ken
dc.contributor.authorCher, Lawrence Men
dc.date.accessioned2015-05-16T01:45:19Z-
dc.date.available2015-05-16T01:45:19Z-
dc.date.issued2014-02-06en
dc.identifier.citationJournal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia 2014; 21(8): 1457-9en
dc.identifier.govdoc24594450en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12107en
dc.description.abstractGranular cell astrocytoma (GCA) is an uncommon malignant glial tumour that is associated with a poor prognosis. GCA cells have some morphological and immunohistochemical similarities to macrophages. In this case, a small biopsy contained no typical astrocytoma and large rounded lesional cells were interpreted as negative for glial fibrillary acidic protein and S100 and positive for CD68, a commonly used marker for macrophages. A diagnosis of a histiocytosis was made. When the patient failed to respond to first and second line therapy, tumour resection was undertaken and the pathology then showed typical morphologic and immunohistochemical features of glioblastoma (astrocytoma World Health Organization grade IV).en
dc.language.isoenen
dc.subject.otherErdheim-Chester diseaseen
dc.subject.otherGliomaen
dc.subject.otherGranular cell astrocytomaen
dc.subject.otherAstrocytoma.diagnosis.metabolism.pathology.surgeryen
dc.subject.otherBiological Markers.metabolismen
dc.subject.otherBiopsyen
dc.subject.otherDiagnosis, Differentialen
dc.subject.otherFatal Outcomeen
dc.subject.otherHistiocytosis.diagnosis.drug therapy.metabolism.pathologyen
dc.subject.otherHumansen
dc.subject.otherImmunohistochemistryen
dc.subject.otherMagnetic Resonance Imagingen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherNeoplasm Gradingen
dc.titleMistaken identity: granular cell astrocytoma masquerading as histiocytosis of the central nervous system.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Clinical Neuroscienceen
dc.identifier.affiliationDepartment of Neurology, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationJoint Austin-Ludwig Oncology Unit, Olivia Newton John Cancer Wellness and Research Centre, Austin Health, Heidelberg, Victoria, Australiaen
dc.identifier.doi10.1016/j.jocn.2013.10.037en
dc.description.pages1457-9en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/24594450en
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