Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/12071
Title: Personal memory function in mild cognitive impairment and subjective memory complaints: results from the Australian Imaging, Biomarkers, and Lifestyle (AIBL) Study of Ageing.
Authors: Buckley, Rachel F;Saling, Michael M;Irish, Muireann;Ames, David;Rowe, Christopher C;Lautenschlager, Nicola T;Maruff, Paul;Macaulay, S Lance;Martins, Ralph N;Masters, Colin L;Rainey-Smith, Stephanie R;Rembach, Alan;Savage, Greg;Szoeke, Cassandra;Ellis, Kathryn A
Affiliation: Melbourne School of Psychological Sciences, University of Melbourne, Melbourne, VIC, Australia The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Neuroscience Research Australia, Sydney, Australia.
National Aging Research Institute, Melbourne, VIC, Australia The Academic Unit for Psychiatry of Old Age, St. Vincent's Health, Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia.
Department of Nuclear Medicine and Centre for PET, Austin Health, Heidelberg, VIC, Australia The Department of Medicine, Austin Health, University of Melbourne, Melbourne, VIC, Australia.
The Academic Unit for Psychiatry of Old Age, St. Vincent's Health, Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia School of Psychiatry and Clinical Neurosciences and West Australian Centre for Health & Ageing, University of Western Australia, WA, Australia.
The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia Cogstate Ltd, Melbourne, VIC, Australia.
Commonwealth Scientific Industrial Research Organization Preventative Health Flagship, Parkville, Australia.
Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical Sciences, Edith Cowan University, WA, Australia Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia School of Psychiatry and Clinical Neurosciences, University of Western Australia, Perth, WA, Australia.
Centre of Excellence for Alzheimer's Disease Research and Care, School of Medical Sciences, Edith Cowan University, WA, Australia Sir James McCusker Alzheimer's Disease Research Unit (Hollywood Private Hospital), Perth, WA, Australia.
The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia.
ARC Centre of Excellence in Cognition and its Disorders, Macquarie University, Sydney, Australia.
National Aging Research Institute, Melbourne, VIC, Australia.
The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, VIC, Australia The Academic Unit for Psychiatry of Old Age, St. Vincent's Health, Department of Psychiatry, University of Melbourne, Melbourne, VIC, Australia.
Issue Date: 2014
Citation: Journal of Alzheimer's Disease : Jad; 40(3): 551-61
Abstract: Autobiographical memory (ABM) refers to the recollection of individual experiences, while personal semantic memory (PSM) refers to personally relevant, but shared, facts. Mild cognitive impairment (MCI) is routinely diagnosed with the aid of neuropsychological tests, which do not tap the ABM and PSM domains.We aimed to characterize the nature of ABM and PSM retrieval in cognitively healthy (HC) memory complainers, non-memory complainers, and MCI participants, and to investigate the relationship between neuropsychological tests and personal memory.Gender- and education-matched participants (HC = 80 and MCI = 43) completed the Episodic ABM Interview (EAMI) and a battery of neuropsychological tests.ABM and PSM did not differ between complainers and non-complainers, but were poorer in MCI participants, after accounting for age and depressive symptomatology. There were significant associations between personal memory and objective memory measures were found in MCI participants, but standard cognitive measures were more sensitive to MCI.Personal memory was compromised in MCI, reflected by lower scores on the EAMI. Memory complaining, assessed by current approaches, did not have an impact on personal memory. Standard subjective questionnaires might not reflect the sorts of concerns that bring individuals to clinical attention. Understanding personal memory function in the elderly may aid in the development of a more sensitive measure of subjective memory concerns.
Internal ID Number: 24496075
URI: http://ahro.austin.org.au/austinjspui/handle/1/12071
DOI: 10.3233/JAD-131820
URL: http://www.ncbi.nlm.nih.gov/pubmed/24496075
Type: Journal Article
Subjects: Aging
Alzheimer dementia
autobiographical memory
cognitive function
episodic memory
mild cognitive impairment
subjective cognitive decline
subjective memory complaint
Aged
Aged, 80 and over
Australia
Biological Markers.metabolism
Case-Control Studies
Depression.etiology
Female
Humans
Life Style
Male
Memory Disorders.diagnosis.etiology
Memory, Episodic
Mild Cognitive Impairment.complications.psychology
Multivariate Analysis
Neuroimaging
Neuropsychological Tests
Appears in Collections:Journal articles

Files in This Item:
There are no files associated with this item.


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.