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Title: Locally extensive angio-invasive Scedosporium prolificans infection following resection for squamous cell lung carcinoma.
Authors: Holmes, Natasha E;Trevillyan, Janine M;Kidd, Sarah E;Leong, Trishe Y-M
Affiliation: Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia
Austin Centre for Infection Research, Austin Health, Heidelberg, VIC 3084, Australia ; Department of Medicine, University of Melbourne, Parkville, VIC 3052, Australia
Department of Anatomical Pathology, Austin Pathology, Heidelberg, VIC 3084, Australia
Mycology Unit, SA Pathology, Women's and Children's Hospital, North Adelaide, SA 5006, Australia
Issue Date: 19-Apr-2013
Citation: Medical Mycology Case Reports 2013; 2(): 98-102
Abstract: We report a case of Scedosporium prolificans infection in a patient following surgery for squamous cell lung carcinoma. Combination therapy with voriconazole and terbinafine was commenced for intrathoracic infection and mycotic vasculitis. In spite of antifungal treatment, he developed culture-positive sternal and rib osteomyelitis four months later. Scedosporiosis is not commonly reported in patients with solid organ malignancies, and this case highlights its aggressive nature and propensity for direct local invasion.
Internal ID Number: 24432228
DOI: 10.1016/j.mmcr.2013.04.001
Type: Journal Article
Subjects: Disseminated
Scedosporium prolificans
Therapeutic drug monitoring
Appears in Collections:Journal articles

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