Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/12004
Title: Low physical activity levels and functional decline in individuals with lung cancer.
Authors: Granger, Catherine L;McDonald, Christine F;Irving, Louis;Clark, Ross A;Gough, Karla;Murnane, Andrew;Mileshkin, Linda;Krishnasamy, Meinir;Denehy, Linda
Affiliation: Department of Physiotherapy, The University of Melbourne, Level 7, Alan Gilbert Building, Parkville, Victoria 3010, Australia; Institute for Breathing and Sleep, Austin Hospital, Heidelberg, Victoria 3084, Australia. Electronic address: catherine.granger@mh.org.au.
Institute for Breathing and Sleep, Austin Hospital, Heidelberg, Victoria 3084, Australia; Department of Respiratory and Sleep Medicine, Austin Hospital, Heidelberg, Victoria 3084, Australia.
Department of Respiratory and Sleep Medicine, Royal Melbourne Hospital, Parkville, Victoria 3010, Australia.
Department of Physiotherapy, The University of Melbourne, Level 7, Alan Gilbert Building, Parkville, Victoria 3010, Australia.
Department of Cancer Experiences Research, Peter MacCallum Cancer Centre, East Melbourne, Victoria 3002, Australia.
Department of Physiotherapy, The University of Melbourne, Level 7, Alan Gilbert Building, Parkville, Victoria 3010, Australia; Institute for Breathing and Sleep, Austin Hospital, Heidelberg, Victoria 3084, Australia.
Issue Date: 26-Nov-2013
Citation: Lung Cancer (amsterdam, Netherlands) 2013; 83(2): 292-9
Abstract: Physical activity has been infrequently measured objectively in non-small cell lung cancer (NSCLC). We aimed to investigate levels of physical activity, functional and patient reported outcomes at diagnosis and over six months in participants with recently diagnosed NSCLC and compare results with both physical activity guidelines and outcomes of similar-aged healthy individuals.This prospective observational study assessed 50 individuals from three Australian tertiary hospitals with stage I-IIIB NSCLC at diagnosis, then 10 weeks and six months later. Thirty five healthy individuals without cancer were assessed once. Outcome measures included tri-axial accelerometery (number of steps per day), six minute walk distance (6MWD), muscle strength and questionnaires including health-related quality of life (HRQoL).Individuals with NSCLC were engaged in significantly less physical activity than similar-aged healthy individuals, with 60% not meeting physical activity guidelines. At diagnosis they had worse quadriceps strength, nutritional status and HRQoL. Over six months, participants with NSCLC experienced decline in self-reported physical activity, 6MWD and muscle strength, and worsening symptoms.At diagnosis individuals with NSCLC engage in less physical activity, are weaker and more depressed than healthy individuals and their self-reported physical activity declines over six months. Future studies are required to investigate the efficacy of interventions to increase physical activity.
Internal ID Number: 24360323
URI: http://ahro.austin.org.au/austinjspui/handle/1/12004
DOI: 10.1016/j.lungcan.2013.11.014
URL: http://www.ncbi.nlm.nih.gov/pubmed/24360323
Type: Journal Article
Subjects: Accelerometery
Functional decline
Health-related quality of life
Lung cancer
Physical activity
Accelerometry
Aged
Australia
Carcinoma, Non-Small-Cell Lung.physiopathology
Female
Follow-Up Studies
Humans
Lung Neoplasms.physiopathology
Male
Middle Aged
Motor Activity
Muscle Strength
Neoplasm Staging
Prospective Studies
Quality of Life
Questionnaires
Self Report
Walking
Appears in Collections:Journal articles

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