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|Title:||Preoperative urinary neutrophil gelatinase-associated lipocalin and outcome in high-risk heart failure patients undergoing cardiac surgery.|
|Authors:||Silvetti, Simona;Meroni, Roberta;Bignami, Elena;Bove, Tiziana;Landoni, Giovanni;Zangrillo, Alberto;Bellomo, Rinaldo;Pappalardo, Federico|
|Affiliation:||Departments of Intensive Care and Cardiac Surgery, Austin Health, Melbourne, Australia|
Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milano, Italy.
Department of Anesthesia and Intensive Care, San Raffaele Scientific Institute, Milano, Italy. Electronic address: email@example.com.
|Citation:||Journal of Cardiothoracic and Vascular Anesthesia 2013; 28(2): 323-7|
|Abstract:||To investigate the ability of early urinary neutrophil gelatinase-associated lipocalin to predict postoperative complications in adult patients with ventricular dysfunction undergoing cardiac surgery.Prospective observational study.Single-center study, university hospital.Fifty-six adult high-risk cardiac surgical patients with preoperative cardiac failure.None.Demographic and clinical characteristics were obtained, and neutrophil gelatinase-associated lipocalin was measured at baseline and at several time points after surgery. Patient characteristics and neutrophil gelatinase-associated lipocalin levels were related to renal and patient outcome. On multivariate analyses, preoperative urinary neutrophil gelatinase-associated lipocalin was an independent predictor of length of intensive care stay (p = 0.004) and in-hospital stay (p = 0.04), but not of acute kidney injury or renal replacement therapy and was not associated with baseline renal function.In a cohort of high-risk cardiac surgery patients, preoperative urinary neutrophil gelatinase-associated lipocalin value provided prognostic information that was independent of the onset of acute kidney injury or of preoperative renal function.|
|Internal ID Number:||24295718|
|Subjects:||acute kidney injury|
neutrophil gelatinase-associated lipocalin
Acute Kidney Injury.urine
Aged, 80 and over
Cardiac Output, Low.etiology
Cardiac Surgical Procedures.methods
Cardiotonic Agents.therapeutic use
Intra-Aortic Balloon Pumping
Kidney Function Tests
Length of Stay
Predictive Value of Tests
Renal Replacement Therapy
|Appears in Collections:||Journal articles|
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