Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11971
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dc.contributor.authorTomasini, Arnaud-
dc.contributor.authorFrançois, Patrice-
dc.contributor.authorHowden, Benjamin P-
dc.contributor.authorFechter, Pierre-
dc.contributor.authorRomby, Pascale-
dc.contributor.authorCaldelari, Isabelle-
dc.date.accessioned2015-05-16T01:36:22Z-
dc.date.available2015-05-16T01:36:22Z-
dc.date.issued2013-11-27-
dc.identifier.citationInfection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases 2013; 21(): 616-26en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11971en
dc.description.abstractRNA molecules with regulatory functions in pathogenic bacteria have benefited from a renewed interest these two last decades. In Staphylococcus aureus, recent genome-wide approaches have led to the discovery that almost 10-20% of genes code for RNAs with critical regulatory roles in adaptive processes. These RNAs include trans-acting RNAs, which mostly act through binding to target mRNAs, and cis-acting RNAs, which include regulatory regions of mRNAs responding to various metabolic signals. Besides recent analysis of S. aureus transcriptome has revealed an unprecedented existence of pervasive transcription generating a high number of weakly expressed antisense RNAs along the genome as well as numerous mRNAs with overlapped regions. Here, we will illustrate the diversity of trans-acting RNAs and illustrate how they are integrated into complex regulatory circuits, which link metabolism, stress response and virulence.en_US
dc.language.isoenen
dc.subject.otherRegulatory RNAen
dc.subject.otherStaphylococcusen
dc.subject.otherVirulenceen
dc.subject.otherGene Expression Regulation, Bacterialen
dc.subject.otherRNA, Bacterial.genetics.metabolismen
dc.subject.otherRNA, Small Untranslated.genetics.metabolismen
dc.subject.otherStaphylococcus aureus.genetics.pathogenicityen
dc.subject.otherStress, Physiologicalen
dc.subject.otherVirulence Factors.geneticsen
dc.titleThe importance of regulatory RNAs in Staphylococcus aureus.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleInfection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseasesen_US
dc.identifier.affiliationMicrobiologyen_US
dc.identifier.affiliationInfectious Diseasesen_US
dc.identifier.affiliationDepartment of Microbiology, Monash University, Clayton, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Microbiology and Immunology, University of Melbourne, Parkville, Victoria, Australiaen_US
dc.identifier.affiliationArchitecture et Réactivité de l'ARN, Université de Strasbourg, CNRS, IBMC, Strasbourg, France.en_US
dc.identifier.affiliationGenomic Research Laboratory, Department of Medical Specialties, Geneva University Hospitals, University of Geneva, Genève, Switzerland.en_US
dc.identifier.affiliationArchitecture et Réactivité de l'ARN, Université de Strasbourg, CNRS, IBMC, Strasbourg, Franceen_US
dc.identifier.doi10.1016/j.meegid.2013.11.016en_US
dc.description.pages616-26en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24291227en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherHowden, Benjamin P
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptMicrobiology-
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