Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11868
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGundlach, Andrew Len
dc.contributor.authorWisden, Wen
dc.contributor.authorMorris, B Jen
dc.contributor.authorHunt, S Pen
dc.date.accessioned2015-05-16T01:29:54Z
dc.date.available2015-05-16T01:29:54Z
dc.date.issued1990-07-13en
dc.identifier.citationNeuroscience Letters; 114(3): 241-7en
dc.identifier.govdoc2402333en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11868en
dc.description.abstractGalanin is a peptide containing 29 amino acid residues that is present in both the central and peripheral nervous systems. Galanin has multiple putative biological functions including regulation of hormone release, stimulation of feeding behaviour, and effects on blood pressure. This study examined the distribution of neurones expressing preprogalanin mRNA in the rat brain by in situ hybridization of a specific 35S-labelled oligonucleotide. Preprogalanin mRNA was detected in several regions of brain, with high concentrations in the paraventricular, periventricular, supraoptic, dorsomedial and arcuate nuclei of the hypothalamus; the locus coeruleus and dorsal raphe nucleus in the pons; and the nucleus tractus solitarii and ventrolateral reticular nucleus in the medulla. These findings are consistent with studies of the cellular localization of galanin-like immunoreactivity in rat brain, and further suggest the involvement of galanin in the regulation of several functions ranging from water balance to blood pressure control.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherBrain Chemistryen
dc.subject.otherGalaninen
dc.subject.otherNucleic Acid Hybridizationen
dc.subject.otherOligonucleotides.diagnostic useen
dc.subject.otherPeptides.analysis.geneticsen
dc.subject.otherProtein Precursors.analysis.geneticsen
dc.subject.otherRNA Probesen
dc.subject.otherRNA, Messenger.analysisen
dc.subject.otherRatsen
dc.titleLocalization of preprogalanin mRNA in rat brain: in situ hybridization study with a synthetic oligonucleotide probe.en
dc.typeJournal Articleen
dc.identifier.journaltitleNeuroscience lettersen
dc.identifier.affiliationUniversity of Melbourne Clinical Pharmacology and Therapeutics Unit, Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages241-7en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2402333en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

4
checked on Mar 28, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.