Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11786
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dc.contributor.authorTeichtahl, Andrew Jen
dc.contributor.authorWluka, Anita Een
dc.contributor.authorWang, Yuanyuanen
dc.contributor.authorStrauss, Boyd Jen
dc.contributor.authorProietto, Josephen
dc.contributor.authorDixon, John Ben
dc.contributor.authorJones, Graemeen
dc.contributor.authorForbes, Andrewen
dc.contributor.authorKouloyan-Ilic, Susanen
dc.contributor.authorMartel-Pelletier, Johanneen
dc.contributor.authorPelletier, Jean-Pierreen
dc.contributor.authorCicuttini, Flavia Men
dc.date.accessioned2015-05-16T01:24:50Z
dc.date.available2015-05-16T01:24:50Z
dc.date.issued2013-06-06en
dc.identifier.citationAnnals of the Rheumatic Diseases 2013; 73(9): 1652-8en
dc.identifier.govdoc23744978en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11786en
dc.description.abstractMeniscal tears are commonly found on MRI and increase the risk for radiographic knee osteoarthritis (OA). While meniscectomy is recommended when knee pain is severe or functionally disabling, it is unclear how to best treat meniscal tears without these symptoms. The aim of this longitudinal study was to examine the effect of weight change on knee cartilage and pain in a cohort of community-based adults with and without meniscal tears detected by MRI.250 adults with no history of knee OA or knee injury were recruited from the general community and weight-loss clinics. MRI of the knee, Western Ontario and McMaster University Osteoarthritis Index (WOMAC), weight and height were measured at baseline and again at follow-up approximately 2 years later.Medial meniscal tears were present in 36 (18%) of the cohort. In those with medial meniscal tears, after adjustment for confounders, percentage weight change was significantly associated with percentage change in medial tibial cartilage volume (β 0.2% 95% CI 0.08% to 0.3% p=0.002) and knee pain (β 11.6% 95% CI 2.1% to 21.1% p=0.02). That is, for every 1% gain in weight, there was an associated 0.2% increased loss of medial tibial cartilage volume and 11.6% increase in pain. In those with no medial meniscal tear, neither change in medial tibial cartilage volume (β 0.02% 95% CI -0.01% to 0.10% p=0.53) or pain (β 1.9% 95% CI -2.2% to 6.1% p=0.36) were significantly associated with change in weight.This study demonstrated that among adults with medial meniscal tears, weight gain is associated with increased cartilage loss and pain, while weight loss is associated with the converse. This suggests attention to weight is particularly important in the management of people with medial meniscal tears.en
dc.language.isoenen
dc.subject.otherKnee Osteoarthritisen
dc.subject.otherMagnetic Resonance Imagingen
dc.subject.otherOsteoarthritisen
dc.subject.otherAdulten
dc.subject.otherAnthropometry.methodsen
dc.subject.otherBody Weight.physiologyen
dc.subject.otherCartilage, Articular.pathologyen
dc.subject.otherDisease Progressionen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherKnee Injuries.complications.pathology.physiopathologyen
dc.subject.otherLongitudinal Studiesen
dc.subject.otherMagnetic Resonance Imaging.methodsen
dc.subject.otherMaleen
dc.subject.otherMenisci, Tibial.injuriesen
dc.subject.otherMiddle Ageden
dc.subject.otherPain.etiology.pathology.physiopathologyen
dc.subject.otherPain Measurement.methodsen
dc.subject.otherWeight Gain.physiologyen
dc.subject.otherWeight Loss.physiologyen
dc.titleThe longitudinal relationship between changes in body weight and changes in medial tibial cartilage, and pain among community-based adults with and without meniscal tears.en
dc.typeJournal Articleen
dc.identifier.journaltitleAnnals of the rheumatic diseasesen
dc.identifier.affiliationMenzies Research Institute, Hobart, Tasmania, Australiaen
dc.identifier.affiliationDepartment of Medicine, Body Composition Laboratory, Monash Medical Centre, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Radiology, Alfred Hospital, Melbourne, Tasmania, Australiaen
dc.identifier.affiliationOsteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, Quebec, Canadaen
dc.identifier.affiliationBaker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australiaen
dc.identifier.affiliationDepartment of Medicine, University of Melbourne and Austin Hospital, Melbourne, Victoria, Australiaen
dc.identifier.doi10.1136/annrheumdis-2013-203210en
dc.description.pages1652-8en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/23744978en
dc.type.austinJournal Articleen
local.name.researcherProietto, Joseph
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptMedicine (University of Melbourne)-
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