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Title: Acute haemolytic reaction due to anti-Wb: a case report.
Authors: Wright, T;Brown, P;Marais, I;Hong, F S
Affiliation: Austin Pathology, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 17-May-2013
Citation: Vox Sanguinis 2013; 105(4): 355-7
Abstract: A 73-year-old Greek woman presented with symptomatic anaemia requiring red cell transfusion in the setting of progressive chronic lymphocytic leukaemia (CLL). Based on a negative antibody screen, two units of red blood cells (RBCs) were provided for transfusion. During the transfusion, the patient developed an acute haemolytic transfusion reaction (HTR), but recovered with supportive measures. Subsequent antibody investigation confirmed that the patient had an anti-Wb antibody and that the implicated RBC unit was Wb-positive. This is the first report of an anti-Wb causing a clinically significant acute HTR in the literature.
Internal ID Number: 23679095
DOI: 10.1111/vox.12052
Type: Journal Article
Subjects: Gerbich antigens
Wb antigen
acute haemolytic transfusion reaction
Blood Group Antigens.immunology
Blood Group Incompatibility.diagnosis.immunology
Erythrocyte Transfusion.adverse effects
Appears in Collections:Journal articles

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