Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/11725
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dc.contributor.authorHowell, Jessicaen
dc.contributor.authorVisvanathan, Kumaren
dc.date.accessioned2015-05-16T01:21:02Z
dc.date.available2015-05-16T01:21:02Z
dc.date.issued2013-04-04en
dc.identifier.citationAntiviral Therapy 2013; 18(7): 853-65en
dc.identifier.govdoc23559549en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/11725en
dc.description.abstractHCV infection is an exponentially growing health burden worldwide, with an estimated 170 million people infected. Although therapies for HCV are continually improving, there remain a considerable proportion of patients who do not achieve viral eradication and develop liver disease. Natural killer (NK) cells are crucial for T-cell activation and are one of the first-line sentinel cell responders to viral infection. A recent explosion in studies exploring the role of NK cells in HCV infection has yielded important mechanistic information and intriguing potential therapeutic options for HCV infection. This review provides a general overview of normal NK cell function and outlines some of the important mechanisms characterizing the immune interplay between NK cells and HCV infection.en
dc.language.isoenen
dc.subject.otherAdaptive Immunityen
dc.subject.otherHepacivirus.immunologyen
dc.subject.otherHepatitis C.complications.immunology.metabolismen
dc.subject.otherHepatitis C, Chronicen
dc.subject.otherHumansen
dc.subject.otherImmunity, Innateen
dc.subject.otherKiller Cells, Natural.immunology.metabolismen
dc.subject.otherLiver.immunology.pathologyen
dc.subject.otherLiver Cirrhosis.etiologyen
dc.subject.otherLymphocyte Activation.immunologyen
dc.subject.otherNatural Killer T-Cells.immunology.metabolismen
dc.subject.otherReceptors, Natural Killer Cell.metabolismen
dc.subject.otherReceptors, Pattern Recognition.metabolismen
dc.titleThe role of natural killer cells in hepatitis C infection.en
dc.typeJournal Articleen
dc.identifier.journaltitleAntiviral therapyen
dc.identifier.affiliationmanukascarlet@yahoo.com.en
dc.identifier.affiliationLiver Transplant Unit, Austin Hospital, Melbourne, Australiaen
dc.identifier.doi10.3851/IMP2565en
dc.description.pages853-65en
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pubmed/23559549en
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