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dc.contributor.authorHowell, Jessicaen
dc.contributor.authorVisvanathan, Kumaren
dc.identifier.citationAntiviral Therapy 2013; 18(7): 853-65en
dc.description.abstractHCV infection is an exponentially growing health burden worldwide, with an estimated 170 million people infected. Although therapies for HCV are continually improving, there remain a considerable proportion of patients who do not achieve viral eradication and develop liver disease. Natural killer (NK) cells are crucial for T-cell activation and are one of the first-line sentinel cell responders to viral infection. A recent explosion in studies exploring the role of NK cells in HCV infection has yielded important mechanistic information and intriguing potential therapeutic options for HCV infection. This review provides a general overview of normal NK cell function and outlines some of the important mechanisms characterizing the immune interplay between NK cells and HCV infection.en
dc.subject.otherAdaptive Immunityen
dc.subject.otherHepatitis C.complications.immunology.metabolismen
dc.subject.otherHepatitis C, Chronicen
dc.subject.otherImmunity, Innateen
dc.subject.otherKiller Cells, Natural.immunology.metabolismen
dc.subject.otherLiver Cirrhosis.etiologyen
dc.subject.otherLymphocyte Activation.immunologyen
dc.subject.otherNatural Killer T-Cells.immunology.metabolismen
dc.subject.otherReceptors, Natural Killer Cell.metabolismen
dc.subject.otherReceptors, Pattern Recognition.metabolismen
dc.titleThe role of natural killer cells in hepatitis C infection.en
dc.typeJournal Articleen
dc.identifier.journaltitleAntiviral therapyen
dc.identifier.affiliationLiver Transplant Unit, Austin Hospital, Melbourne, Australiaen
Appears in Collections:Journal articles

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