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|Title:||The role of natural killer cells in hepatitis C infection.|
|Authors:||Howell, Jessica;Visvanathan, Kumar|
Liver Transplant Unit, Austin Hospital, Melbourne, Australia
|Citation:||Antiviral Therapy 2013; 18(7): 853-65|
|Abstract:||HCV infection is an exponentially growing health burden worldwide, with an estimated 170 million people infected. Although therapies for HCV are continually improving, there remain a considerable proportion of patients who do not achieve viral eradication and develop liver disease. Natural killer (NK) cells are crucial for T-cell activation and are one of the first-line sentinel cell responders to viral infection. A recent explosion in studies exploring the role of NK cells in HCV infection has yielded important mechanistic information and intriguing potential therapeutic options for HCV infection. This review provides a general overview of normal NK cell function and outlines some of the important mechanisms characterizing the immune interplay between NK cells and HCV infection.|
|Internal ID Number:||23559549|
Hepatitis C, Chronic
Killer Cells, Natural.immunology.metabolism
Natural Killer T-Cells.immunology.metabolism
Receptors, Natural Killer Cell.metabolism
Receptors, Pattern Recognition.metabolism
|Appears in Collections:||Journal articles|
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