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|Title:||Cortical excitability and refractory epilepsy: a three-year longitudinal transcranial magnetic stimulation study.|
|Authors:||Badawy, Radwa A B;Jackson, Graeme D;Berkovic, Samuel F;Macdonell, Richard A L|
|Affiliation:||Department of Neurology, Austin Health, Heidelberg, Epilepsy Research Centre, Australia|
|Citation:||International Journal of Neural Systems 2012; 23(1): 1250030|
|Abstract:||Transcranial magnetic stimulation was used to study the effect of recurrent seizures on cortical excitability over time in epilepsy. 77 patients with firm diagnoses of idiopathic generalized epilepsy (IGE) or focal epilepsy were repeatedly evaluated over three years. At onset, all groups had increased cortical excitability. At the end of follow-up the refractory group was associated with a broad increase in cortical excitability. Conversely, cortical excitability decreased in all seizure free groups after introduction of an effective medication.|
|Internal ID Number:||23273126|
Cerebral Cortex.drug effects.physiopathology
Epilepsies, Partial.drug therapy.physiopathology.therapy
Evoked Potentials, Motor.physiology
Transcranial Magnetic Stimulation.instrumentation.methods
|Appears in Collections:||Journal articles|
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