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Title: Faecal microbiota transplantation for severe Clostridium difficile infection in the intensive care unit.
Authors: Trubiano, Jason A;Gardiner, Bradley;Kwong, Jason C;Ward, Peter;Testro, Adam G;Charles, Patrick G P
Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 1-Feb-2013
Citation: European Journal of Gastroenterology and Hepatology; 25(2): 255-7
Abstract: We describe a case of faecal microbiota transplantation (FMT) used for severe binary toxin-positive Clostridium difficile infection in an intensive care setting. The patient was admitted to the ICU of a tertiary hospital and failed traditional maximal pharmacological management. Adjunctive therapy with FMT given through gastroscopy resulted in resolution of the C. difficile-related symptoms. Although there is a growing experience with FMT for recurrent C. difficile infection, published evidence in severe disease is very limited. In a landscape of increasingly severe C. difficile infection, adjunctive FMT may be considered a useful early treatment option.
Internal ID Number: 23117471
DOI: 10.1097/MEG.0b013e32835b2da9
Type: Journal Article
Subjects: Aged
Clostridium difficile
Combined Modality Therapy
Enterocolitis, Pseudomembranous.therapy
Fatal Outcome
Intensive Care.methods
Appears in Collections:Journal articles

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