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Title: Steady state plasma [3H]-noradrenaline kinetics in quadriplegic chronic spinal cord injury patients.
Authors: Krum, Henry;Brown, Douglas J;Rowe, P R;Louis, William J;Howes, L G
Affiliation: Clinical Pharmacology and Therapeutics Unit, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 1-Aug-1990
Citation: Journal of Autonomic Pharmacology; 10(4): 221-6
Abstract: 1. Steady state plasma noradrenaline kinetics were measured in eight male quadriplegic patients and in eight age and sex matched controls. 2. Plasma noradrenaline levels were significantly lower in quadriplegic patients compared to controls. Noradrenaline spillover rate was markedly reduced in quadriplegics compared to controls while noradrenaline clearance was similar in both groups. 3. Noradrenaline kinetics in quadriplegic patients differ from peripheral autonomic neuropathy patients where reductions in both the spillover and clearance of noradrenaline are present.
Internal ID Number: 2229099
Type: Journal Article
Subjects: Adult
Blood Pressure.drug effects
Spinal Cord Injuries.blood.complications
Tritium.diagnostic use
Appears in Collections:Journal articles

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