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|Title:||Comparison of immunoglobulin G subclass concentrations in severe community-acquired pneumonia and severe pandemic 2009 influenza A (H1N1) infection.|
|Authors:||Gordon, Claire L;Holmes, Natasha E;Grayson, M Lindsay;Torresi, Joseph;Johnson, Paul D R;Cheng, Allen C;Charles, Patrick G P|
|Affiliation:||Department of Infectious Diseases, Austin Health, Melbourne, Australia.|
|Citation:||Clinical and Vaccine Immunology : Cvi 2012; 19(3): 446-8|
|Abstract:||We compared immunoglobulin G (IgG) subclasses in patients with severe noninfluenza community-acquired pneumonia (CAP) to those in patients with severe pandemic 2009 influenza (H1N1) virus infection. Low IgG1 and IgG2 levels occurred often in the CAP group; however, H1N1 patients had lower IgG1 and IgG2 levels (5.4 versus 3.3 g/liter [P = 0.008] and 2.5 versus 1.2 g/liter [P < 0.001], respectively). Low IgG2 levels may be specifically linked to severe H1N1; however, it is not clear whether this association is related to H1N1 or to other features of severity.|
|Internal ID Number:||22237894|
Influenza A Virus, H1N1 Subtype.isolation & purification
|Appears in Collections:||Journal articles|
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