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Title: Decreased body weight in young Osterix-Cre transgenic mice results in delayed cortical bone expansion and accrual.
Authors: Davey, Rachel A;Clarke, Michele V;Sastra, Stephen;Skinner, Jarrod P;Chiang, Cherie Ying;Anderson, Paul H;Zajac, Jeffrey D
Affiliation: Department of Medicine, Austin Health, University of Melbourne, Studley Road, Heidelberg, VIC 3084, Australia
Issue Date: 13-Dec-2011
Citation: Transgenic Research 2011; 21(4): 885-93
Abstract: Conditional gene inactivation using the Cre/loxP system has lead to significant advances in our understanding of the function of genes in a wide range of disciplines. It is becoming increasingly apparent in the literature, that Cre transgenic mice may themselves have a phenotype. In the following study we describe the bone phenotype of a commonly used Cre transgenic mouse line to study osteoblasts, the Osx-GFP
Internal ID Number: 22160436
DOI: 10.1007/s11248-011-9581-z
Type: Journal Article
Subjects: Animals
Body Weight.genetics.physiology
Bone Development.genetics.physiology
Bone and Bones.physiology.radiography
Mice, Transgenic.genetics.physiology
Transcription Factors.genetics.metabolism
Appears in Collections:Journal articles

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