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dc.contributor.authorOgrin, Rajnaen
dc.contributor.authorWoodward, Michael Men
dc.contributor.authorSussman, Geoffen
dc.contributor.authorKhalil, Zeinaben
dc.identifier.citationInternational Wound Journal; 8(5): 437-45en
dc.description.abstractSuccessful wound healing requires adequate transcutaneous oxygen tension (tcpO(2) ). TcpO(2) may not commonly be incorporated in clinical assessments because of variable measurement response at different sensory temperatures. This study aims to assess the relationship between changes in tcpO(2) , measured under basal (39°C) and stimulated (44°C) conditions and healing rate of chronic wounds over 4 weeks, to determine whether tcpO(2) measurement can predict delayed wound healing. TcpO(2) (Radiometer TCM400) measurements at sensor temperatures 39 and 44°C were recorded (twice, 4 weeks apart) adjacent to the ulcer site, and at a mirror image site on the contralateral leg. Ulcer outline was traced on clear acetate and perimeter and area measured (Visitrak™, Smith and Nephew). TcpO(2) measured at 44 and 39°C adjacent to all 13 wounds were lower compared to the contralateral site, significant at 44°C (P = 0·008). Significant correlation (r(2) = 0·8) occurred between wound healing rate and increased tcpO(2) at 44°C over 4 weeks. Importantly, the ratio of 39/44°C tcpO(2) , measured at the initial appointment, appeared to predict normal or delayed healing rate. TcpO(2) may provide clinicians with information regarding anticipated healing ability of wounds at the initial appointment, and hence identify wounds requiring early implementation of adjuvant therapies to accelerate healing.en
dc.subject.otherBlood Gas Monitoring, Transcutaneous.methodsen
dc.subject.otherFollow-Up Studiesen
dc.subject.otherFoot Ulcer.metabolism.physiopathologyen
dc.subject.otherPredictive Value of Testsen
dc.subject.otherWound Healingen
dc.titleOxygen tension assessment: an overlooked tool for prediction of delayed healing in a clinical setting.en
dc.typeJournal Articleen
dc.identifier.journaltitleInternational wound journalen
dc.identifier.affiliationEndocrine Centre of Excellence, Heidelberg Repatriation Hospital, Austin Health Heidelberg, Melbourne, Australiaen
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