Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/11319
Title: Prophylaxis against postsplenectomy pneumococcal infection.
Authors: Siddins, M;Downie, J;Wise, K;O'Reilly, M
Affiliation: Department of Surgery, Austin Hospital, Heidelberg, Victoria, Australia.
Issue Date: 1-Mar-1990
Citation: Australian and New Zealand Journal of Surgery; 60(3): 183-7
Abstract: An excess risk of overwhelming sepsis following splenectomy is well established. In view of this, surgical responsibility must embrace the administration of pneumococcal prophylaxis. Current recommendations vary, but routine pneumococcal vaccination, together with penicillin prophylaxis in selected patients, is advocated widely. This retrospective review of 75 patients undergoing splenectomy was undertaken in order to evaluate the extent to which current practice complies with these recommendations. Among surviving patients, the incidence of vaccination with polyvalent pneumococcal vaccine (PPV) was found to vary according to operative indication. All haematological patients received pre-operative PPV. Two-thirds of multitrauma patients were vaccinated, while 42% of patients who required splenectomy following accidental intra-operative trauma received PPV. Only 11% of patients who underwent incidental splenectomy were vaccinated. Long-term antibiotic prophylaxis was commenced in 33% of surviving patients under 20 years of age, and in 8% with underlying malignancy. These results highlight a need for greater vigilance in the administration of pneumococcal prophylaxis, particularly following accidental or incidental splenectomy.
Internal ID Number: 2183753
URI: http://ahro.austin.org.au/austinjspui/handle/1/11319
URL: http://www.ncbi.nlm.nih.gov/pubmed/2183753
Type: Journal Article
Subjects: Adult
Aged
Bacterial Vaccines.therapeutic use
Child
Female
Hematologic Diseases.surgery
Humans
Male
Middle Aged
Penicillins.therapeutic use
Pneumococcal Infections.prevention & control
Retrospective Studies
Spleen.injuries
Splenectomy
Streptococcus pneumoniae.immunology
Vaccination
Appears in Collections:Journal articles

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