Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/11277
Title: Liver transplantation rapidly stops cerebral ammonia uptake in fulminant hepatic failure.
Authors: Glassford, Neil J;Farley, K J;Warrillow, Stephen J;Bellomo, Rinaldo
Affiliation: Department of Intensive Care, Austin Hospital, Melbourne, VIC, Australia.
Issue Date: 1-Jun-2011
Citation: Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine; 13(2): 113-8
Abstract: This report describes the effect of liver transplantation on transcerebral ammonia uptake in a case of fulminant hepatic failure. A young woman with fulminant hepatic failure and coma received monitoring of transcerebral ammonia uptake before and after orthotopic liver transplantation. Before liver transplantation, median transcerebral ammonia uptake was 8 µmol/L. After liver transplantation, ammonia uptake decreased to 0 µmol/L. Fulminant hepatic failure is associated with transcerebral ammonia uptake, which is fully and rapidly corrected by liver transplantation.
Internal ID Number: 21627580
URI: http://ahro.austin.org.au/austinjspui/handle/1/11277
URL: http://www.ncbi.nlm.nih.gov/pubmed/21627580
Type: Journal Article
Subjects: Adult
Ammonia.metabolism
Brain.metabolism
Female
Follow-Up Studies
Hepatic Encephalopathy.etiology.metabolism.surgery
Humans
Liver Failure, Acute.complications.metabolism.surgery
Liver Transplantation.methods
Appears in Collections:Journal articles

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