Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11193
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dc.contributor.authorJackson, Melinda Len
dc.contributor.authorHughes, Matthew Een
dc.contributor.authorCroft, Rodney Jen
dc.contributor.authorHoward, Mark Een
dc.contributor.authorCrewther, Daviden
dc.contributor.authorKennedy, Gerard Aen
dc.contributor.authorOwens, Katherineen
dc.contributor.authorPierce, Robert Jen
dc.contributor.authorO'Donoghue, Fergal Jen
dc.contributor.authorJohnston, Patricken
dc.date.accessioned2015-05-16T00:46:53Z
dc.date.available2015-05-16T00:46:53Z
dc.date.issued2011-06-01en
dc.identifier.citationBrain Imaging and Behavior; 5(2): 97-108en
dc.identifier.govdoc21271311en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11193en
dc.description.abstractSleep loss, widespread in today's society and associated with a number of clinical conditions, has a detrimental effect on a variety of cognitive domains including attention. This study examined the sequelae of sleep deprivation upon BOLD fMRI activation during divided attention. Twelve healthy males completed two randomized sessions; one after 27 h of sleep deprivation and one after a normal night of sleep. During each session, BOLD fMRI was measured while subjects completed a cross-modal divided attention task (visual and auditory). After normal sleep, increased BOLD activation was observed bilaterally in the superior frontal gyrus and the inferior parietal lobe during divided attention performance. Subjects reported feeling significantly more sleepy in the sleep deprivation session, and there was a trend towards poorer divided attention task performance. Sleep deprivation led to a down regulation of activation in the left superior frontal gyrus, possibly reflecting an attenuation of top-down control mechanisms on the attentional system. These findings have implications for understanding the neural correlates of divided attention and the neurofunctional changes that occur in individuals who are sleep deprived.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherAttentionen
dc.subject.otherBrain.blood supply.physiopathologyen
dc.subject.otherFrontal Lobe.blood supplyen
dc.subject.otherHumansen
dc.subject.otherMagnetic Resonance Imagingen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherOxygen.blooden
dc.subject.otherParietal Lobe.blood supplyen
dc.subject.otherSleep Deprivation.diagnosis.physiopathology.psychologyen
dc.titleThe effect of sleep deprivation on BOLD activity elicited by a divided attention task.en
dc.typeJournal Articleen
dc.identifier.journaltitleBrain imaging and behavioren
dc.identifier.affiliationInstitute for Breathing and Sleep, Austin Health, Melbourne, Australiaen
dc.identifier.doi10.1007/s11682-011-9115-6en
dc.description.pages97-108en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/21271311en
dc.type.austinJournal Articleen
local.name.researcherHoward, Mark E
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextWith Fulltext-
item.grantfulltextopen-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptRespiratory and Sleep Medicine-
crisitem.author.deptInstitute for Breathing and Sleep-
crisitem.author.deptRespiratory and Sleep Medicine-
crisitem.author.deptInstitute for Breathing and Sleep-
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